MGP Database

MGP000371

Ontology/Pathway Information

Entrez Gene ID	760
Gene Name	carbonic anhydrase II
Gene Symbol	CA2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0045177	IDA:UniProtKB	C	apical part of cell
GO:0030424	IEA:Ensembl	C	axon
GO:0016323	IEA:Ensembl	C	basolateral plasma membrane
GO:0005737	IDA:UniProtKB	C	cytoplasm
GO:0005829	TAS:Reactome	C	cytosol
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005902	IEA:Ensembl	C	microvillus
GO:0043209	IEA:Ensembl	C	myelin sheath
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0004089	TAS:ProtInc	F	carbonate dehydratase activity
GO:0008270	IDA:UniProtKB	F	zinc ion binding
GO:0038166	IDA:UniProtKB	P	angiotensin-activated signaling pathway
GO:0015701	TAS:Reactome	P	bicarbonate transport
GO:0071498	IEA:Ensembl	P	cellular response to fluid shear stress
GO:0001822	IEA:Ensembl	P	kidney development
GO:0002009	IEA:Ensembl	P	morphogenesis of an epithelium
GO:0042475	IEA:Ensembl	P	odontogenesis of dentin-containing tooth
GO:0006730	IEA:InterPro	P	one-carbon metabolic process
GO:0045780	IEA:Ensembl	P	positive regulation of bone resorption
GO:0032849	IEA:Ensembl	P	positive regulation of cellular pH reduction
GO:2001150	ISS:UniProtKB	P	positive regulation of dipeptide transmembrane transport
GO:0045672	IEA:Ensembl	P	positive regulation of osteoclast differentiation
GO:0032230	IEA:Ensembl	P	positive regulation of synaptic transmission, GABAergic
GO:0044070	IDA:UniProtKB	P	regulation of anion transport
GO:2001225	IEA:Ensembl	P	regulation of chloride transport
GO:0051453	ISS:UniProtKB	P	regulation of intracellular pH
GO:0043627	IEA:Ensembl	P	response to estrogen
GO:0009268	IEA:Ensembl	P	response to pH
GO:0010043	IEA:Ensembl	P	response to zinc ion
GO:0046903	IEA:Ensembl	P	secretion
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_121329	Erythrocytes take up carbon dioxide and release oxygen
REACT_121380	Erythrocytes take up oxygen and release carbon dioxide
REACT_111217	Metabolism
REACT_120969	O2/CO2 exchange in erythrocytes
REACT_121123	Reversible hydration of carbon dioxide