MGP Database

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MGP000406

Ontology/Pathway Information

Entrez Gene ID821
Gene Namecalnexin
Gene Symbol CANX
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 IEA:EnsemblCaxon
GO:0032839 IEA:EnsemblCdendrite cytoplasm
GO:0043197 IEA:EnsemblCdendritic spine
GO:0005783 IDA:UniProtKBCendoplasmic reticulum
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005789 IDA:MGICendoplasmic reticulum membrane
GO:0044233 IDA:MGICER-mitochondrion membrane contact site
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0071556 TAS:ReactomeCintegral component of lumenal side of endoplasmic reticulum membrane
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0043025 IEA:EnsemblCneuronal cell body
GO:0043234 IEA:EnsemblCprotein complex
GO:0005840 IEA:EnsemblCribosome
GO:0005791 IEA:EnsemblCrough endoplasmic reticulum
GO:0005790 IEA:EnsemblCsmooth endoplasmic reticulum
GO:0005509 TAS:ProtIncFcalcium ion binding
GO:0030246 IEA:UniProtKB-KWFcarbohydrate binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0007568 IEA:EnsemblPaging
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0061077 IEA:EnsemblPchaperone-mediated protein folding
GO:0072583 ISS:UniProtKBPclathrin-mediated endocytosis
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0006457 TAS:ReactomePprotein folding
GO:0018279 TAS:ReactomePprotein N-linked glycosylation via asparagine
GO:0009306 TAS:ProtIncPprotein secretion
GO:0048488 ISS:UniProtKBPsynaptic vesicle endocytosis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_75795Antigen Presentation: Folding, assembly and peptide loading of class I MHC
REACT_22426Asparagine N-linked glycosylation
REACT_6277Assembly of Viral Components at the Budding Site
REACT_23810Calnexin/calreticulin cycle
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_268132Defective ALG11 causes ALG11-CDG (CDG-1p)
REACT_267773Defective ALG12 causes ALG12-CDG (CDG-1g)
REACT_268645Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)
REACT_268144Defective ALG1 causes ALG1-CDG (CDG-1k)
REACT_268833Defective ALG2 causes ALG2-CDG (CDG-1i)
REACT_268185Defective ALG3 causes ALG3-CDG (CDG-1d)
REACT_267765Defective ALG6 causes ALG6-CDG (CDG-1c)
REACT_268459Defective ALG8 causes ALG8-CDG (CDG-1h)
REACT_268015Defective ALG9 causes ALG9-CDG (CDG-1l)
REACT_268438Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)
REACT_268849Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
REACT_268813Defective MAN1B1 causes MRT15
REACT_268600Defective MGAT2 causes MGAT2-CDG (CDG-2a)
REACT_267905Defective MOGS causes MOGS-CDG (CDG-2b)
REACT_268619Defective MPDU1 causes MPDU1-CDG (CDG-1f)
REACT_268458Defective RFT1 causes RFT1-CDG (CDG-1n)
REACT_116125Disease
REACT_267875Diseases associated with N-glycosylation of proteins
REACT_268324Diseases of glycosylation
REACT_6900Immune System
REACT_6167Influenza Infection
REACT_6145Influenza Life Cycle
REACT_17015Metabolism of proteins
REACT_121399MHC class II antigen presentation
REACT_23878N-glycan trimming in the ER and Calnexin/Calreticulin cycle
REACT_22161Post-translational protein modification
REACT_6270Virus Assembly and Release
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