MGP Database

MGP000425

Ontology/Pathway Information

Entrez Gene ID	847
Gene Name	catalase
Gene Symbol	CAT
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005829	IEA:Ensembl	C	cytosol
GO:0005783	IEA:Ensembl	C	endoplasmic reticulum
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005925	IDA:UniProtKB	C	focal adhesion
GO:0005794	IEA:Ensembl	C	Golgi apparatus
GO:0043231	IDA:HPA	C	intracellular membrane-bounded organelle
GO:0005764	IEA:Ensembl	C	lysosome
GO:0016020	IDA:UniProtKB	C	membrane
GO:0005758	IEA:Ensembl	C	mitochondrial intermembrane space
GO:0005782	TAS:Reactome	C	peroxisomal matrix
GO:0005778	ISS:UniProtKB	C	peroxisomal membrane
GO:0005777	IDA:UniProtKB	C	peroxisome
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0004046	IEA:Ensembl	F	aminoacylase activity
GO:0016209	IDA:UniProtKB	F	antioxidant activity
GO:0004096	IDA:UniProtKB	F	catalase activity
GO:0019899	IPI:UniProtKB	F	enzyme binding
GO:0020037	IDA:UniProtKB	F	heme binding
GO:0046872	IEA:UniProtKB-KW	F	metal ion binding
GO:0050661	IDA:UniProtKB	F	NADP binding
GO:0016684	ISS:UniProtKB	F	oxidoreductase activity, acting on peroxide as acceptor
GO:0042803	IDA:UniProtKB	F	protein homodimerization activity
GO:0005102	IPI:UniProtKB	F	receptor binding
GO:0009060	IEA:Ensembl	P	aerobic respiration
GO:0007568	IEA:Ensembl	P	aging
GO:0071363	IEA:Ensembl	P	cellular response to growth factor stimulus
GO:0008203	IEA:Ensembl	P	cholesterol metabolic process
GO:0020027	IEA:Ensembl	P	hemoglobin metabolic process
GO:0042744	IDA:UniProtKB	P	hydrogen peroxide catabolic process
GO:0043066	IMP:UniProtKB	P	negative regulation of apoptotic process
GO:0032088	IEA:Ensembl	P	negative regulation of NF-kappaB transcription factor activity
GO:0055086	TAS:Reactome	P	nucleobase-containing small molecule metabolic process
GO:0001649	IDA:UniProtKB	P	osteoblast differentiation
GO:0051781	IEA:UniProtKB-KW	P	positive regulation of cell division
GO:0051092	IEA:Ensembl	P	positive regulation of NF-kappaB transcription factor activity
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0051289	IDA:UniProtKB	P	protein homotetramerization
GO:0051262	IDA:UniProtKB	P	protein tetramerization
GO:0006144	TAS:Reactome	P	purine nucleobase metabolic process
GO:0006195	TAS:Reactome	P	purine nucleotide catabolic process
GO:0055093	IEA:Ensembl	P	response to hyperoxia
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0000302	IMP:UniProtKB	P	response to reactive oxygen species
GO:0033197	IEA:Ensembl	P	response to vitamin E
GO:0044281	TAS:Reactome	P	small molecule metabolic process
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process
GO:0001657	IEA:Ensembl	P	ureteric bud development
GO:0009650	IMP:UniProtKB	P	UV protection

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_120956	Cellular responses to stress
REACT_264249	Detoxification of Reactive Oxygen Species
REACT_111217	Metabolism
REACT_1698	Metabolism of nucleotides
REACT_2086	Purine catabolism
REACT_522	Purine metabolism

SMP Pathway Links

SMP ID	Description
SMP00468	Degradation of Superoxides
SMP00429	Disulfiram Action Pathway
SMP00449	Ethanol Degradation
SMP00063	Tryptophan Metabolism