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MGP000431

Record overview

MGPD IDMGP000431
Gene ID873
SpeciesHomo sapiens (Human)
Gene Namecarbonyl reductase 1
Gene Symbol CBR1
SynonymsCBR; hCBR1; SDR21C1;
Alternate namescarbonyl reductase [NADPH] 1; 15-hydroxyprostaglandin dehydrogenase; NADPH-dependent carbonyl reductase 1; carbonyl reductase (NADPH) 1; prostaglandin 9-ketoreductase; prostaglandin-E(2) 9-reductase; short chain dehydrogenase/reductase family 21C, member 1;
Chromosome21
Map Location21q22.13
EC Number1.1.1.184
SummaryThe protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]
OrthologsView orthologs and multiple alignments for CBR1

Proteins

carbonyl reductase [NADPH] 1 isoform 1
Refseq ID:NP_001748
Protein GI:4502599
UniProt ID:P16152
mRNA ID:NM_001757
Length:277
RefSeq Status:
MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADP
TPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIG
VTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW
 
carbonyl reductase [NADPH] 1 isoform 2
Refseq ID:NP_001273718
Protein GI:557948119
UniProt ID:P16152
mRNA ID:NM_001286789
Length:173
RefSeq Status:
MSSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADP
TPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQASCVLSAWSCLSQNPSGGKSKPLAWFTEMSIICRCLTLGPF
 
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