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MGP000432

Record overview

MGPD IDMGP000432
Gene ID874
SpeciesHomo sapiens (Human)
Gene Namecarbonyl reductase 3
Gene Symbol CBR3
SynonymshCBR3; SDR21C2; HEL-S-25;
Alternate namescarbonyl reductase [NADPH] 3; carbonyl reductase (NADPH) 3; epididymis secretory protein Li 25; NADPH-dependent carbonyl reductase 3; short chain dehydrogenase/reductase family 21C, member 2;
Chromosome21
Map Location21q22.2
EC Number1.1.1.184
SummaryCarbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CBR3

Proteins

carbonyl reductase [NADPH] 3
Refseq ID:NP_001227
Protein GI:4502601
UniProt ID:O75828
mRNA ID:NM_001236
Length:277
RefSeq Status:
MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDP
MPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPNSPYGVSKLG
VTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW
 
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