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MGP000437

Record overview

MGPD IDMGP000437
Gene ID887
SpeciesHomo sapiens (Human)
Gene Namecholecystokinin B receptor
Gene Symbol CCKBR
SynonymsGASR; CCK-B; CCK2R;
Alternate namesgastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; CCK2 receptor; CCK2-R; cholecystokinin-2 receptor; gastrin receptor;
Chromosome11
Map Location11p15.4
SummaryThis gene encodes a G-protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CCKBR

Proteins

gastrin/cholecystokinin type B receptor
Refseq ID:NP_795344
Protein GI:28875799
UniProt ID:P32239
mRNA ID:NM_176875
Length:447
RefSeq Status:
MELLKLNRSVQGTGPGPGASLCRPGAPLLNSSSVGNLSCEPPRIRGAGTRELELAIRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSD
LLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVIVATWLLSGLLMVPYPVYTVVQPVGP
RVLQCVHRWPSARVRQTWSVLLLLLLFFIPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGEDSDGCYVQLPRS
RPALELTALTAPGPGSGSRPTQAKLLAKKRVVRMLLVIVVLFFLCWLPVYSANTWRAFDGPGAHRALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQA
CLETCARCCPRPPRARPRALPDEDPPTPSIASLSRLSYTTISTLGPG
 
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