MGP Database

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MGP000437

Ontology/Pathway Information

Entrez Gene ID887
Gene Namecholecystokinin B receptor
Gene Symbol CCKBR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005887 IC:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0046935 TAS:ProtIncF1-phosphatidylinositol-3-kinase regulator activity
GO:0004951 TAS:ProtIncFcholecystokinin receptor activity
GO:0015054 IDA:UniProtKBFgastrin receptor activity
GO:0004435 TAS:ProtIncFphosphatidylinositol phospholipase C activity
GO:0031741 IDA:NTNU_SBFtype B gastrin/cholecystokinin receptor binding
GO:0008283 TAS:ProtIncPcell proliferation
GO:0007166 NAS:UniProtKBPcell surface receptor signaling pathway
GO:0038188 TAS:GOCPcholecystokinin signaling pathway
GO:0007586 TAS:ProtIncPdigestion
GO:0048565 IEA:EnsemblPdigestive tract development
GO:0007631 TAS:ProtIncPfeeding behavior
GO:0001696 IEA:EnsemblPgastric acid secretion
GO:0048732 IEA:EnsemblPgland development
GO:0008152 TAS:GOCPmetabolic process
GO:0007200 TAS:ProtIncPphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0008284 IDA:UniProtKBPpositive regulation of cell proliferation
GO:0007204 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0043551 TAS:GOCPregulation of phosphatidylinositol 3-kinase activity
GO:0007600 TAS:ProtIncPsensory perception
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00736Betazole Action Pathway
SMP00232Cimetidine Action Pathway
SMP00225Esomeprazole Action Pathway
SMP00231Famotidine Action Pathway
SMP00589Gastric Acid Production
SMP00227Lansoprazole Action Pathway
SMP00735Metiamide Action Pathway
SMP00233Nizatidine Action Pathway
SMP00226Omeprazole Action Pathway
SMP00228Pantoprazole Action Pathway
SMP00246Pirenzepine Action Pathway
SMP00229Rabeprazole Action Pathway
SMP00230Ranitidine Action Pathway
SMP00734Roxatidine acetate Action Pathway
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