MGP Database

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MGP000443

Ontology/Pathway Information

Entrez Gene ID898
Gene Namecyclin E1
Gene Symbol CCNE1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0000307 IEA:EnsemblCcyclin-dependent protein kinase holoenzyme complex
GO:0005829 TAS:ReactomeCcytosol
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:HPACnucleus
GO:0050681 NAS:UniProtKBFandrogen receptor binding
GO:0016538 IEA:EnsemblFcyclin-dependent protein serine/threonine kinase regulator activity
GO:0016301 IEA:EnsemblFkinase activity
GO:0003713 NAS:UniProtKBFtranscription coactivator activity
GO:0030521 NAS:UniProtKBPandrogen receptor signaling pathway
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0006270 IEA:EnsemblPDNA replication initiation
GO:0000082 NAS:UniProtKBPG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0045893 NAS:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0006468 IMP:MGIPprotein phosphorylation
GO:0000079 IEA:InterProPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000083 TAS:ReactomePregulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0016055 IEA:EnsemblPWnt signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_120956Cellular responses to stress
REACT_169274Cellular Senescence
REACT_9029Cyclin A:Cdk2-associated events at S phase entry
REACT_1574Cyclin E associated events during G1/S transition
REACT_169185DNA Damage/Telomere Stress Induced Senescence
REACT_471E2F mediated regulation of DNA replication
REACT_111214G0 and Early G1
REACT_2254G1/S DNA Damage Checkpoints
REACT_683G1/S-Specific Transcription
REACT_1783G1/S Transition
REACT_21267Mitotic G1-G1/S phases
REACT_1625p53-Dependent G1 DNA Damage Response
REACT_85p53-Dependent G1/S DNA damage checkpoint
REACT_308Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes
REACT_9003SCF(Skp2)-mediated degradation of p27/p21
REACT_899S Phase
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