MGP Database

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MGP000449

Ontology/Pathway Information

Entrez Gene ID915
Gene NameCD3d molecule, delta (CD3-TCR complex)
Gene Symbol CD3D
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042105 IEA:EnsemblCalpha-beta T cell receptor complex
GO:0005737 NAS:UniProtKBCcytoplasm
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042101 NAS:UniProtKBCT cell receptor complex
GO:0046982 IPI:UniProtKBFprotein heterodimerization activity
GO:0003713 IDA:MGIFtranscription coactivator activity
GO:0004888 IC:UniProtKBFtransmembrane signaling receptor activity
GO:0007166 IC:UniProtKBPcell surface receptor signaling pathway
GO:0045944 IDA:MGIPpositive regulation of transcription from RNA polymerase II promoter
GO:0045059 ISS:UniProtKBPpositive thymic T cell selection
GO:0050776 TAS:ReactomePregulation of immune response
GO:0031295 TAS:ReactomePT cell costimulation
GO:0030217 IDA:MGIPT cell differentiation
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_19344Costimulation by the CD28 family
REACT_12555Downstream TCR signaling
REACT_12623Generation of second messenger molecules
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_19324PD-1 signaling
REACT_12582Phosphorylation of CD3 and TCR zeta chains
REACT_12526TCR signaling
REACT_12596Translocation of ZAP-70 to Immunological synapse
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