MGP Database

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MGP000451

Ontology/Pathway Information

Entrez Gene ID917
Gene NameCD3g molecule, gamma (CD3-TCR complex)
Gene Symbol CD3G
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0042105 IEA:EnsemblCalpha-beta T cell receptor complex
GO:0005887 NAS:UniProtKBCintegral component of plasma membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042101 NAS:UniProtKBCT cell receptor complex
GO:0046982 IPI:UniProtKBFprotein heterodimerization activity
GO:0030159 NAS:UniProtKBFreceptor signaling complex scaffold activity
GO:0042608 NAS:UniProtKBFT cell receptor binding
GO:0004888 IMP:UniProtKBFtransmembrane signaling receptor activity
GO:0007166 IMP:UniProtKBPcell surface receptor signaling pathway
GO:0007163 IMP:UniProtKBPestablishment or maintenance of cell polarity
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS:ReactomePinnate immune response
GO:0006461 NAS:UniProtKBPprotein complex assembly
GO:0015031 IMP:UniProtKBPprotein transport
GO:0050776 TAS:ReactomePregulation of immune response
GO:0070228 IMP:UniProtKBPregulation of lymphocyte apoptotic process
GO:0042110 NAS:UniProtKBPT cell activation
GO:0031295 TAS:ReactomePT cell costimulation
GO:0050852 TAS:ReactomePT cell receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_19344Costimulation by the CD28 family
REACT_12555Downstream TCR signaling
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_160274FCGR activation
REACT_12623Generation of second messenger molecules
REACT_6900Immune System
REACT_11152Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACT_6802Innate Immune System
REACT_19324PD-1 signaling
REACT_12582Phosphorylation of CD3 and TCR zeta chains
REACT_160086Regulation of actin dynamics for phagocytic cup formation
REACT_160158Role of phospholipids in phagocytosis
REACT_12526TCR signaling
REACT_12596Translocation of ZAP-70 to Immunological synapse
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