MGP Database

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MGP000461

Ontology/Pathway Information

Entrez Gene ID948
Gene NameCD36 molecule (thrombospondin receptor)
Gene Symbol CD36
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:BHF-UCLCcell surface
GO:0030666 TAS:ReactomeCendocytic vesicle membrane
GO:0009897 IEA:EnsemblCexternal side of plasma membrane
GO:0005615 IDA:UniProtKBCextracellular space
GO:0005794 IEA:EnsemblCGolgi apparatus
GO:0005887 TAS:BHF-UCLCintegral component of plasma membrane
GO:0016020 TAS:ProtIncCmembrane
GO:0045121 IEA:EnsemblCmembrane raft
GO:0045335 TAS:ReactomeCphagocytic vesicle
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0031092 TAS:ReactomeCplatelet alpha granule membrane
GO:0008035 IEA:EnsemblFhigh-density lipoprotein particle binding
GO:0008289 IDA:BHF-UCLFlipid binding
GO:0071813 IDA:UniProtKBFlipoprotein particle binding
GO:0070892 IEA:EnsemblFlipoteichoic acid receptor activity
GO:0030169 IDA:BHF-UCLFlow-density lipoprotein particle binding
GO:0005041 IMP:BHF-UCLFlow-density lipoprotein receptor activity
GO:0070053 ISS:BHF-UCLFthrombospondin receptor activity
GO:0050431 ISS:BHF-UCLFtransforming growth factor beta binding
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0043277 IEA:EnsemblPapoptotic cell clearance
GO:0007596 TAS:ReactomePblood coagulation
GO:0007155 TAS:ProtIncPcell adhesion
GO:0007166 IEA:EnsemblPcell surface receptor signaling pathway
GO:0044255 TAS:ReactomePcellular lipid metabolic process
GO:0071221 IEA:EnsemblPcellular response to bacterial lipopeptide
GO:0071447 IEA:EnsemblPcellular response to hydroperoxide
GO:0071222 IEA:EnsemblPcellular response to lipopolysaccharide
GO:0071223 IEA:EnsemblPcellular response to lipoteichoic acid
GO:0019934 IDA:BHF-UCLPcGMP-mediated signaling
GO:0030301 ISS:BHF-UCLPcholesterol transport
GO:0050830 IEA:EnsemblPdefense response to Gram-positive bacterium
GO:0045087 TAS:ReactomePinnate immune response
GO:0006629 NAS:ProtIncPlipid metabolic process
GO:0019915 IMP:BHF-UCLPlipid storage
GO:0042953 IMP:BHF-UCLPlipoprotein transport
GO:0044539 IDA:UniProtKBPlong-chain fatty acid import
GO:0034383 IMP:BHF-UCLPlow-density lipoprotein particle clearance
GO:0055096 IEA:EnsemblPlow-density lipoprotein particle mediated signaling
GO:0002755 TAS:ReactomePMyD88-dependent toll-like receptor signaling pathway
GO:0044130 IEA:EnsemblPnegative regulation of growth of symbiont in host
GO:0042992 IEA:EnsemblPnegative regulation of transcription factor import into nucleus
GO:0000122 IEA:EnsemblPnegative regulation of transcription from RNA polymerase II promoter
GO:0007263 IDA:BHF-UCLPnitric oxide mediated signal transduction
GO:0006910 IEA:EnsemblPphagocytosis, recognition
GO:0034381 ISS:BHF-UCLPplasma lipoprotein particle clearance
GO:0015911 IDA:BHF-UCLPplasma membrane long-chain fatty acid transport
GO:0030168 TAS:ReactomePplatelet activation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0030194 IEA:EnsemblPpositive regulation of blood coagulation
GO:2000334 IEA:EnsemblPpositive regulation of blood microparticle formation
GO:0001954 IDA:BHF-UCLPpositive regulation of cell-matrix adhesion
GO:0010886 IEA:EnsemblPpositive regulation of cholesterol storage
GO:0043123 IEA:EnsemblPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0032735 IEA:EnsemblPpositive regulation of interleukin-12 production
GO:0032755 IEA:EnsemblPpositive regulation of interleukin-6 production
GO:0060907 IEA:EnsemblPpositive regulation of macrophage cytokine production
GO:0010744 IMP:BHF-UCLPpositive regulation of macrophage derived foam cell differentiation
GO:0043410 IEA:EnsemblPpositive regulation of MAPK cascade
GO:0050731 IEA:EnsemblPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0060100 IEA:EnsemblPpositive regulation of phagocytosis, engulfment
GO:2000379 IEA:EnsemblPpositive regulation of reactive oxygen species metabolic process
GO:0032760 IEA:EnsemblPpositive regulation of tumor necrosis factor production
GO:2000121 IEA:EnsemblPregulation of removal of superoxide radicals
GO:0035634 IEA:EnsemblPresponse to stilbenoid
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0034134 TAS:ReactomePtoll-like receptor 2 signaling pathway
GO:0034142 TAS:ReactomePtoll-like receptor 4 signaling pathway
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
GO:0038123 TAS:ReactomePtoll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS:ReactomePtoll-like receptor TLR6:TLR2 signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6890Activated TLR4 signalling
REACT_75774Adaptive Immune System
REACT_111119Antigen processing-Cross presentation
REACT_160300Binding and Uptake of Ligands by Scavenger Receptors
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_111174Cross-presentation of particulate exogenous antigens (phagosomes)
REACT_111045Developmental Biology
REACT_22279Fatty acid, triacylglycerol, and ketone body metabolism
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_6788MyD88:Mal cascade initiated on plasma membrane
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_116145PPARA activates gene expression
REACT_19241Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_163679Scavenging by Class B Receptors
REACT_7980Toll Like Receptor 2 (TLR2) Cascade
REACT_6894Toll Like Receptor 4 (TLR4) Cascade
REACT_6966Toll-Like Receptors Cascades
REACT_8005Toll Like Receptor TLR1:TLR2 Cascade
REACT_8006Toll Like Receptor TLR6:TLR2 Cascade
REACT_27161Transcriptional regulation of white adipocyte differentiation
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