MGP Database

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MGP000467

Record overview

MGPD IDMGP000467
Gene ID965
SpeciesHomo sapiens (Human)
Gene NameCD58 molecule
Gene Symbol CD58
Synonymsag3; LFA3; LFA-3;
Alternate nameslymphocyte function-associated antigen 3; surface glycoprotein LFA-3; CD58 antigen, (lymphocyte function-associated antigen 3);
Chromosome1
Map Location1p13
SummaryThis gene encodes a member of the immunoglobulin superfamily. The encoded protein is a ligand of the T lymphocyte CD2 protein, and functions in adhesion and activation of T lymphocytes. The protein is localized to the plasma membrane. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
OrthologsView orthologs and multiple alignments for CD58

Proteins

lymphocyte function-associated antigen 3 isoform 1
Refseq ID:NP_001770
Protein GI:4502677
UniProt ID:P19256
mRNA ID:NM_001779
Length:250
RefSeq Status:
MVAGSDAGRALGVLSVVCLLHCFGFISCFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDE
DEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSI
ILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTNSN
 
lymphocyte function-associated antigen 3 isoform 2
Refseq ID:NP_001138294
Protein GI:221316575
UniProt ID:P19256
mRNA ID:NM_001144822
Length:248
RefSeq Status:
MVAGSDAGRALGVLSVVCLLHCFGFISCFSQQIYGVVYGNVTFHVPSNVPLKEVLWKKQKDKVAELENSEFRAFSSFKNRVYLDTVSGSLTIYNLTSSDE
DEYEMESPNITDTMKFFLYVLESLPSPTLTCALTNGSIEVQCMIPEHYNSHRGLIMYSWDCPMEQCKRNSTSIYFKMENDLPQKIQCTLSNPLFNTTSSI
ILTTCIPSSGHSRHRYALIPIPLAVITTCIVLYMNGILKCDRKPDRTK
 
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