MGP Database

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MGP000468

Ontology/Pathway Information

Entrez Gene ID966
Gene NameCD59 molecule, complement regulatory protein
Gene Symbol CD59
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031362 IDA:MGICanchored component of external side of plasma membrane
GO:0009986 IDA:UniProtKBCcell surface
GO:0043218 IEA:EnsemblCcompact myelin
GO:0005576 IBA:RefGenomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0016020 TAS:ProtIncCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0042383 IEA:EnsemblCsarcolemma
GO:0031982 IDA:UniProtKBCvesicle
GO:0001848 IBA:RefGenomeFcomplement binding
GO:0007596 TAS:ProtIncPblood coagulation
GO:0001775 IBA:RefGenomePcell activation
GO:0007166 TAS:ProtIncPcell surface receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0001971 IEA:EnsemblPnegative regulation of activation of membrane attack complex
GO:0043066 IEA:EnsemblPnegative regulation of apoptotic process
GO:0042102 IEA:EnsemblPpositive regulation of T cell proliferation
GO:0030449 TAS:ReactomePregulation of complement activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6932Complement cascade
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_118707Regulation of Complement cascade
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