MGP Database

MGP000473

Record overview

MGPD ID	MGP000473
Gene ID	974
Species	Homo sapiens (Human)
Gene Name	CD79b molecule, immunoglobulin-associated beta
Gene Symbol	CD79B
Synonyms	B29; IGB; AGM6;
Alternate names	B-cell antigen receptor complex-associated protein beta chain; Ig-beta; B-cell-specific glycoprotein B29; immunoglobulin-associated B29 protein; CD79b antigen (immunoglobulin-associated beta);
Chromosome	17
Map Location	17q23
Summary	The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Orthologs	View orthologs and multiple alignments for CD79B

Proteins

B-cell antigen receptor complex-associated protein beta chain isoform 1 precursor

Refseq ID:	NP_000617
Protein GI:	11038674
UniProt ID:	P40259
mRNA ID:	NM_000626
Length:	229
RefSeq Status:

`MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQ NESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLD IDQTATYEDIVTLRTGEVKWSVGEHPGQE`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAEPVPA

mat_peptide: 29..125
product: B-cell antigen receptor complex-associated protein beta chain isoform 2
calculated_mol_wt: 11065
peptide sequence: 
ARSEDRYRNPKGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAEPVPA

mat_peptide: 29..229
product: B-cell antigen receptor complex-associated protein beta chain isoform 1
calculated_mol_wt: 23082
peptide sequence: 
ARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNN
TSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQ
E

B-cell antigen receptor complex-associated protein beta chain isoform 2 precursor

Refseq ID:	NP_067613
Protein GI:	11038676
UniProt ID:	P40259
mRNA ID:	NM_021602
Length:	125
RefSeq Status:

`MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQT ATYEDIVTLRTGEVKWSVGEHPGQE`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAEPVPA

mat_peptide: 29..125
product: B-cell antigen receptor complex-associated protein beta chain isoform 2
calculated_mol_wt: 11065
peptide sequence: 
ARSEDRYRNPKGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE

B-cell antigen receptor complex-associated protein beta chain isoform 3 precursor

Refseq ID:	NP_001035022
Protein GI:	90193592
UniProt ID:	P40259
mRNA ID:	NM_001039933
Length:	230
RefSeq Status:

`MARLALSPVPSHWMVALLLLLSAAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEES QNESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGL DIDQTATYEDIVTLRTGEVKWSVGEHPGQE`

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAEPVPA

mat_peptide: 29..125
product: B-cell antigen receptor complex-associated protein beta chain isoform 2
calculated_mol_wt: 11065
peptide sequence: 
ARSEDRYRNPKGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQE

sig_peptide: 1..28
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAEPVPA

mat_peptide: 29..229
product: B-cell antigen receptor complex-associated protein beta chain isoform 1
calculated_mol_wt: 23082
peptide sequence: 
ARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNN
TSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPGQ
E

sig_peptide: 1..28
calculated_mol_wt: 2984
peptide sequence: 
MARLALSPVPSHWMVALLLLLSAAEPVP

mat_peptide: 29..230
product: B-cell antigen receptor complex-associated protein beta chain isoform 3
calculated_mol_wt: 23153
peptide sequence: 
AARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCN
NTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSKAGMEEDHTYEGLDIDQTATYEDIVTLRTGEVKWSVGEHPG
QE