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MGP000522

Record overview

MGPD IDMGP000522
Gene ID1051
SpeciesHomo sapiens (Human)
Gene NameCCAAT/enhancer binding protein (C/EBP), beta
Gene Symbol CEBPB
SynonymsTCF5; IL6DBP; NF-IL6; C/EBP-beta;
Alternate namesCCAAT/enhancer-binding protein beta; nuclear factor NF-IL6; transcription factor 5; nuclear factor of interleukin 6; interleukin 6-dependent DNA-binding protein;
Chromosome20
Map Location20q13.1
SummaryThis intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]
OrthologsView orthologs and multiple alignments for CEBPB

Proteins

CCAAT/enhancer-binding protein beta isoform a
Refseq ID:NP_005185
Protein GI:28872796
UniProt ID:P17676
mRNA ID:NM_005194
Length:345
RefSeq Status:
MQRLVAWDPACLPLPPPPPAFKSMEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAA
PPAPAPAPASSGQHHDFLSDLFSDDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFEPADCKRKEEAGAPGGGAGMA
AGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQ
HKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSGHC
 
CCAAT/enhancer-binding protein beta isoform b
Refseq ID:NP_001272807
Protein GI:551895085
UniProt ID:P17676
mRNA ID:NM_001285878
Length:322
RefSeq Status:
MEVANFYYEADCLAAAYGGKAAPAAPPAARPGPRPPAGELGSIGDHERAIDFSPYLEPLGAPQAPAPATATDTFEAAPPAPAPAPASSGQHHDFLSDLFS
DDYGGKNCKKPAEYGYVSLGRLGAAKGALHPGCFAPLHPPPPPPPPPAELKAEPGFEPADCKRKEEAGAPGGGAGMAAGFPYALRAYLGYQAVPSGSSGS
LSTSSSSSPPGTPSPADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRE
LSTLRNLFKQLPEPLLASSGHC
 
CCAAT/enhancer-binding protein beta isoform c
Refseq ID:NP_001272808
Protein GI:551895123
UniProt ID:P17676
mRNA ID:NM_001285879
Length:147
RefSeq Status:
MAAGFPYALRAYLGYQAVPSGSSGSLSTSSSSSPPGTPSPADAKAPPTACYAGAAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLE
TQHKVLELTAENERLQKKVEQLSRELSTLRNLFKQLPEPLLASSGHC
 
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