MGP Database

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MGP000549

Ontology/Pathway Information

Entrez Gene ID1129
Gene Namecholinergic receptor, muscarinic 2
Gene Symbol CHRM2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0005887 IDA:UniProtKBCintegral component of plasma membrane
GO:0005886 IDA:LIFEdbCplasma membrane
GO:0045211 IEA:UniProtKB-SubCellCpostsynaptic membrane
GO:0016907 IDA:UniProtKBFG-protein coupled acetylcholine receptor activity
GO:0007188 TAS:ProtIncPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007213 IDA:UniProtKBPG-protein coupled acetylcholine receptor signaling pathway
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0007187 TAS:ProtIncPG-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007399 TAS:ProtIncPnervous system development
GO:0007207 TAS:ProtIncPphospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway
GO:0051482 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0008016 TAS:ProtIncPregulation of heart contraction
GO:0009615 IEP:UniProtKBPresponse to virus
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_16983Amine ligand-binding receptors
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_19231G alpha (i) signalling events
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_16943Muscarinic acetylcholine receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00296Acebutolol Action Pathway
SMP00297Alprenolol Action Pathway
SMP00665Amiodarone Action Pathway
SMP00376Amlodipine Action Pathway
SMP00664Arbutamine Action Pathway
SMP00298Atenolol Action Pathway
SMP00299Betaxolol Action Pathway
SMP00668Bevantolol Action Pathway
SMP00300Bisoprolol Action Pathway
SMP00657Bopindolol Action Pathway
SMP00670Bupranolol Action Pathway
SMP00658Carteolol Action Pathway
SMP00367Carvedilol Action Pathway
SMP00359Diltiazem Action Pathway
SMP00325Disopyramide Action Pathway
SMP00662Dobutamine Action Pathway
SMP00661Epinephrine Action Pathway
SMP00301Esmolol Action Pathway
SMP00377Felodipine Action Pathway
SMP00331Flecainide Action Pathway
SMP00326Fosphenytoin (Antiarrhythmic) Action Pathway
SMP00332Ibutilide Action Pathway
SMP00663Isoprenaline Action Pathway
SMP00378Isradipine Action Pathway
SMP00368Labetalol Action Pathway
SMP00666Levobunolol Action Pathway
SMP00328Lidocaine (Antiarrhythmic) Action Pathway
SMP00667Metipranolol Action Pathway
SMP00302Metoprolol Action Pathway
SMP00329Mexiletine Action Pathway
SMP00588Muscle/Heart Contraction
SMP00303Nadolol Action Pathway
SMP00366Nebivolol Action Pathway
SMP00379Nifedipine Action Pathway
SMP00380Nimodipine Action Pathway
SMP00381Nisoldipine Action Pathway
SMP00382Nitrendipine Action Pathway
SMP00304Oxprenolol Action Pathway
SMP00305Penbutolol Action Pathway
SMP00327Phenytoin (Antiarrhythmic) Action Pathway
SMP00306Pindolol Action Pathway
SMP00669Practolol Action Pathway
SMP00324Procainamide (Antiarrhythmic) Action Pathway
SMP00307Propranolol Action Pathway
SMP00323Quinidine Action Pathway
SMP00660Sotalol Action Pathway
SMP00659Timolol Action Pathway
SMP00330Tocainide Action Pathway
SMP00375Verapamil Action Pathway
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