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MGP000569

Record overview

MGPD IDMGP000569
Gene ID1158
SpeciesHomo sapiens (Human)
Gene Namecreatine kinase, muscle
Gene Symbol CKM
SynonymsCKMM; M-CK;
Alternate namescreatine kinase M-type; creatine kinase M chain;
Chromosome19
Map Location19q13.32
EC Number2.7.3.2
SummaryThe protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CKM

Proteins

creatine kinase M-type
Refseq ID:NP_001815
Protein GI:21536288
UniProt ID:P06732
mRNA ID:NM_001824
Length:381
RefSeq Status:
MPFGNTHNKFKLNYKPEEEYPDLSKHNNHMAKVLTLELYKKLRDKETPSGFTVDDVIQTGVDNPGHPFIMTVGCVAGDEESYEVFKELFDPIISDRHGGY
KPTDKHKTDLNHENLKGGDDLDPNYVLSSRVRTGRSIKGYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSP
LLLASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGHPFMWNQHLGYVLTCPSNLGTGLRGGVHVKLA
HLSKHPKFEEILTRLRLQKRGTGGVDTAAVGSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKKLEKGQSIDDMIPAQK
 
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