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MGP000575

Record overview

MGPD IDMGP000575
Gene ID1174
SpeciesHomo sapiens (Human)
Gene Nameadaptor-related protein complex 1, sigma 1 subunit
Gene Symbol AP1S1
SynonymsAP19; EKV3; CLAPS1; MEDNIK; SIGMA1A;
Alternate namesAP-1 complex subunit sigma-1A; sigma1A-adaptin; HA1 19 kDa subunit; clathrin coat assembly protein AP19; adaptor protein complex AP-1 subunit sigma-1A; golgi adaptor HA1/AP1 adaptin sigma-1A subunit; sigma1A subunit of AP-1 clathrin adaptor complex; adapter-related protein complex 1 sigma-1A subunit; adaptor-related protein complex 1 subunit sigma-1A; clathrin assembly protein complex 1 sigma-1A small chain; clathrin-associated/assembly/adaptor protein, small 1 (19kD);
Chromosome7
Map Location7q22.1
SummaryThe protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for AP1S1

Proteins

AP-1 complex subunit sigma-1A
Refseq ID:NP_001274
Protein GI:4557471
UniProt ID:P61966
mRNA ID:NM_001283
Length:158
RefSeq Status:
MMRFMLLFSRQGKLRLQKWYLATSDKERKKMVRELMQVVLARKPKMCSFLEWRDLKVVYKRYASLYFCCAIEGQDNELITLELIHRYVELLDKYFGSVCE
LDIIFNFEKAYFILDEFLMGGDVQDTSKKSVLKAIEQADLLQEEDESPRSVLEEMGLA
 
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