MGP Database

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MGP000575

Ontology/Pathway Information

Entrez Gene ID1174
Gene Nameadaptor-related protein complex 1, sigma 1 subunit
Gene Symbol AP1S1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030121 TAS:UniProtKBCAP-1 adaptor complex
GO:0005905 IEA:UniProtKB-SubCellCcoated pit
GO:0030659 TAS:ReactomeCcytoplasmic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0005765 TAS:ReactomeClysosomal membrane
GO:0016020 IDA:UniProtKBCmembrane
GO:0032588 TAS:ReactomeCtrans-Golgi network membrane
GO:0008565 IEA:InterProFprotein transporter activity
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0006886 IEA:InterProPintracellular protein transport
GO:0061024 TAS:ReactomePmembrane organization
GO:0006892 TAS:ReactomePpost-Golgi vesicle-mediated transport
GO:0006898 TAS:UniProtKBPreceptor-mediated endocytosis
GO:0050690 TAS:ReactomePregulation of defense response to virus by virus
GO:0009615 IEP:UniProtKBPresponse to virus
GO:0016032 TAS:ReactomePviral process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_19187Clathrin derived vesicle budding
REACT_116125Disease
REACT_19400Golgi Associated Vesicle Biogenesis
REACT_6185HIV Infection
REACT_6288Host Interactions of HIV factors
REACT_6900Immune System
REACT_19287Lysosome Vesicle Biogenesis
REACT_11123Membrane Trafficking
REACT_121399MHC class II antigen presentation
REACT_11103Nef mediated downregulation of MHC class I complex cell surface expression
REACT_11149Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
REACT_6835The role of Nef in HIV-1 replication and disease pathogenesis
REACT_11235trans-Golgi Network Vesicle Budding
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