MGP Database

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MGP000595

Ontology/Pathway Information

Entrez Gene ID1213
Gene Nameclathrin, heavy chain (Hc)
Gene Symbol CLTC
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030118 NAS:UniProtKBCclathrin coat
GO:0030669 TAS:ReactomeCclathrin-coated endocytic vesicle membrane
GO:0030136 IDA:UniProtKBCclathrin-coated vesicle
GO:0030132 IEA:InterProCclathrin coat of coated pit
GO:0030130 IEA:InterProCclathrin coat of trans-Golgi network vesicle
GO:0071439 IDA:FlyBaseCclathrin complex
GO:0005737 IDA:HPACcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0043234 IDA:MGICprotein complex
GO:0005819 IDA:UniProtKBCspindle
GO:0032588 TAS:ReactomeCtrans-Golgi network membrane
GO:0031982 IDA:UniProtKBCvesicle
GO:0032051 IPI:FlyBaseFclathrin light chain binding
GO:0003725 IDA:MGIFdouble-stranded RNA binding
GO:0044822 IDA:UniProtKBFpoly(A) RNA binding
GO:0019901 ISS:ParkinsonsUK-UCLFprotein kinase binding
GO:0005198 NAS:UniProtKBFstructural molecule activity
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0006886 NAS:UniProtKBPintracellular protein transport
GO:0061024 TAS:ReactomePmembrane organization
GO:0007067 IMP:UniProtKBPmitotic nuclear division
GO:1900126 IDA:UniProtKBPnegative regulation of hyaluronan biosynthetic process
GO:1903077 IMP:UniProtKBPnegative regulation of protein localization to plasma membrane
GO:0001649 IDA:UniProtKBPosteoblast differentiation
GO:0006892 TAS:ReactomePpost-Golgi vesicle-mediated transport
GO:0031623 IMP:BHF-UCLPreceptor internalization
GO:0006898 IMP:UniProtKBPreceptor-mediated endocytosis
GO:0033572 IMP:BHF-UCLPtransferrin transport
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18266Axon guidance
REACT_264224beta-catenin independent WNT signaling
REACT_111045Developmental Biology
REACT_264198EPH-ephrin mediated repulsion of cells
REACT_264068EPH-Ephrin signaling
REACT_11049Formation of annular gap junctions
REACT_11035Gap junction degradation
REACT_9411Gap junction trafficking
REACT_9480Gap junction trafficking and regulation
REACT_11123Membrane Trafficking
REACT_264199PCP/CE pathway
REACT_11045Signaling by Wnt
REACT_111102Signal Transduction
REACT_263890WNT5A-dependent internalization of FZD4
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