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MGP000677

Record overview

MGPD IDMGP000677
Gene ID1382
SpeciesHomo sapiens (Human)
Gene Namecellular retinoic acid binding protein 2
Gene Symbol CRABP2
SynonymsRBP6; CRABP-II;
Alternate namescellular retinoic acid-binding protein 2; cellular retinoic acid-binding protein II;
Chromosome1
Map Location1q21.3
SummaryThis gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]
OrthologsView orthologs and multiple alignments for CRABP2

Proteins

cellular retinoic acid-binding protein 2
Refseq ID:NP_001186652
Protein GI:315013542
UniProt ID:P29373
mRNA ID:NM_001199723
Length:138
RefSeq Status:
MPNFSGNWKIIRSENFEELLKVLGVNVMLRKIAVAAASKPAVEIKQEGDTFYIKTSTTVRTTEINFKVGEEFEEQTVDGRPCKSLVKWESENKMVCEQKL
LKGEGPKTSWTRELTNDGELILTMTADDVVCTRVYVRE
 
cellular retinoic acid-binding protein 2
Refseq ID:NP_001869
Protein GI:4503029
UniProt ID:P29373
mRNA ID:NM_001878
Length:138
RefSeq Status:
Protein sequence is identical to GI:315013542 (mRNA isoform)
 
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