MGP Database

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MGP000685

Ontology/Pathway Information

Entrez Gene ID1398
Gene Namev-crk avian sarcoma virus CT10 oncogene homolog
Gene Symbol CRK
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IC:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 TAS:ProtIncCnucleus
GO:0005886 IEA:UniProtKB-SubCellCplasma membrane
GO:0046875 IPI:UniProtKBFephrin receptor binding
GO:0042169 IPI:UniProtKBFSH2 domain binding
GO:0000186 TAS:ReactomePactivation of MAPKK activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0048013 IDA:UniProtKBPephrin receptor signaling pathway
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0045087 TAS:ReactomePinnate immune response
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0032956 IDA:UniProtKBPregulation of actin cytoskeleton organization
GO:0035020 IEA:EnsemblPregulation of Rac protein signal transduction
GO:0032319 IDA:UniProtKBPregulation of Rho GTPase activity
GO:0006357 TAS:ProtIncPregulation of transcription from RNA polymerase II promoter
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12002ARMS-mediated activation
REACT_75790Cytokine Signaling in Immune system
REACT_17025Downstream signal transduction
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_1195Insulin receptor signalling cascade
REACT_15523Integrin alphaIIb beta3 signaling
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_15381p130Cas linkage to MAPK signaling for integrins
REACT_798Platelet activation, signaling and aggregation
REACT_278Platelet Aggregation (Plug Formation)
REACT_12005Prolonged ERK activation events
REACT_160086Regulation of actin dynamics for phagocytic cup formation
REACT_23787Regulation of signaling by CBL
REACT_508Signal attenuation
REACT_498Signaling by Insulin receptor
REACT_22232Signaling by Interleukins
REACT_16888Signaling by PDGF
REACT_12529Signaling by VEGF
REACT_11061Signalling by NGF
REACT_12058Signalling to ERKs
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
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