MGP Database

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MGP000731

Ontology/Pathway Information

Entrez Gene ID1513
Gene Namecathepsin K
Gene Symbol CTSK
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0036021 TAS:ReactomeCendolysosome lumen
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:BHF-UCLCextracellular space
GO:0005518 IDA:BHF-UCLFcollagen binding
GO:0004197 IDA:BHF-UCLFcysteine-type endopeptidase activity
GO:0008234 TAS:ProtIncFcysteine-type peptidase activity
GO:0001968 IPI:BHF-UCLFfibronectin binding
GO:0043394 IPI:BHF-UCLFproteoglycan binding
GO:0045453 IEA:EnsemblPbone resorption
GO:0030574 IDA:BHF-UCLPcollagen catabolic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0045087 TAS:ReactomePinnate immune response
GO:0001957 IEA:EnsemblPintramembranous ossification
GO:0006508 TAS:ProtIncPproteolysis
GO:0051603 IDA:BHF-UCLPproteolysis involved in cellular protein catabolic process
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_118682Activation of Matrix Metalloproteinases
REACT_75774Adaptive Immune System
REACT_150401Collagen degradation
REACT_118572Degradation of the extracellular matrix
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_121399MHC class II antigen presentation
REACT_6966Toll-Like Receptors Cascades
REACT_118632Trafficking and processing of endosomal TLR
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