MGP Database

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MGP000735

Ontology/Pathway Information

Entrez Gene ID1520
Gene Namecathepsin S
Gene Symbol CTSS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0036021 TAS:ReactomeCendolysosome lumen
GO:0005576 NAS:UniProtKBCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0043202 TAS:ReactomeClysosomal lumen
GO:0005764 IDA:UniProtKBClysosome
GO:0016020 IEA:EnsemblCmembrane
GO:0005518 IDA:BHF-UCLFcollagen binding
GO:0004197 IDA:BHF-UCLFcysteine-type endopeptidase activity
GO:0001968 IPI:BHF-UCLFfibronectin binding
GO:0043236 IDA:BHF-UCLFlaminin binding
GO:0043394 IPI:BHF-UCLFproteoglycan binding
GO:0002250 IEP:UniProtKBPadaptive immune response
GO:0019882 TAS:UniProtKBPantigen processing and presentation
GO:0042590 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0019886 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0002480 TAS:ReactomePantigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent
GO:0002474 TAS:ReactomePantigen processing and presentation of peptide antigen via MHC class I
GO:0034769 IDA:BHF-UCLPbasement membrane disassembly
GO:0097067 IEP:UniProtKBPcellular response to thyroid hormone stimulus
GO:0030574 IDA:BHF-UCLPcollagen catabolic process
GO:0022617 TAS:ReactomePextracellular matrix disassembly
GO:0030198 TAS:ReactomePextracellular matrix organization
GO:0006955 TAS:ProtIncPimmune response
GO:0045087 TAS:ReactomePinnate immune response
GO:0050729 IEA:EnsemblPpositive regulation of inflammatory response
GO:0006508 TAS:ProtIncPproteolysis
GO:0051603 IDA:BHF-UCLPproteolysis involved in cellular protein catabolic process
GO:0002224 TAS:ReactomePtoll-like receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75774Adaptive Immune System
REACT_111119Antigen processing-Cross presentation
REACT_150180Assembly of collagen fibrils and other multimeric structures
REACT_75820Class I MHC mediated antigen processing & presentation
REACT_120729Collagen formation
REACT_118572Degradation of the extracellular matrix
REACT_111168Endosomal/Vacuolar pathway
REACT_118779Extracellular matrix organization
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_121399MHC class II antigen presentation
REACT_6966Toll-Like Receptors Cascades
REACT_118632Trafficking and processing of endosomal TLR
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