MGP Database

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MGP000736

UniProt Annotations

Entry Information
Gene Namecathepsin Z
Protein EntryCATZ_HUMAN
UniProt IDQ9UBR2
SpeciesHuman
Comments
Comment typeDescription
Catalytic ActivityRelease of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity. {ECO:0000269|PubMed:10504234}.
FunctionExhibits carboxy-monopeptidase as well as carboxy- dipeptidase activity.
SimilarityBelongs to the peptidase C1 family. {ECO:0000255|PROSITE-ProRule:PRU10090}.
Subcellular LocationLysosome.
Tissue SpecificityWidely expressed. {ECO:0000269|PubMed:10653163}.
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