MGP Database

MGP000739

Record overview

MGPD IDMGP000739
Gene ID1525
SpeciesHomo sapiens (Human)
Gene Namecoxsackie virus and adenovirus receptor
Gene Symbol CXADR
SynonymsCAR; HCAR; CAR4/6;
Alternate namescoxsackievirus and adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CVB3-binding protein; HCVADR; coxsackievirus B-adenovirus receptor;
Chromosome21
Map Location21q21.1
SummaryThe protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011]
OrthologsView orthologs and multiple alignments for CXADR

Proteins

coxsackievirus and adenovirus receptor isoform 1 precursor
Refseq ID:NP_001329
Protein GI:4503173
UniProt ID:P78310
mRNA ID:NM_001338
Length:365
RefSeq Status:
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS
GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK
NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS
SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..252 product: coxsackievirus and adenovirus receptor isoform 2 calculated_mol_wt: 26148 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..365 product: Coxsackievirus and adenovirus receptor experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P78310.1) calculated_mol_wt: 37978 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV
 
coxsackievirus and adenovirus receptor isoform 2 precursor
Refseq ID:NP_001193992
Protein GI:333470703
UniProt ID:P78310
mRNA ID:NM_001207063
Length:252
RefSeq Status:
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS
GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAV
RPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..252 product: coxsackievirus and adenovirus receptor isoform 2 calculated_mol_wt: 26148 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR
 
coxsackievirus and adenovirus receptor isoform 3 precursor
Refseq ID:NP_001193993
Protein GI:333470707
UniProt ID:P78310
mRNA ID:NM_001207064
Length:200
RefSeq Status:
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS
GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR
 
coxsackievirus and adenovirus receptor isoform 4 precursor
Refseq ID:NP_001193994
Protein GI:333470705
UniProt ID:P78310
mRNA ID:NM_001207065
Length:89
RefSeq Status:
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVGRCATSKEPYVHCQKLHRQ
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..252 product: coxsackievirus and adenovirus receptor isoform 2 calculated_mol_wt: 26148 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..365 product: Coxsackievirus and adenovirus receptor experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P78310.1) calculated_mol_wt: 37978 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..352 product: coxsackievirus and adenovirus receptor isoform 5 calculated_mol_wt: 36885 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..89 product: coxsackievirus and adenovirus receptor isoform 4 calculated_mol_wt: 7914 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVGRCATSKEPYVHCQKLHRQ
 
coxsackievirus and adenovirus receptor isoform 5 precursor
Refseq ID:NP_001193995
Protein GI:333470709
UniProt ID:P78310
mRNA ID:NM_001207066
Length:352
RefSeq Status:
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS
GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK
NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS
SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..252 product: coxsackievirus and adenovirus receptor isoform 2 calculated_mol_wt: 26148 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..365 product: Coxsackievirus and adenovirus receptor experiment: experimental evidence, no additional details recorded note: propagated from UniProtKB/Swiss-Prot (P78310.1) calculated_mol_wt: 37978 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV sig_peptide: 1..19 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 2071 peptide sequence: MALLLCFVLLCGVVDFARS mat_peptide: 20..352 product: coxsackievirus and adenovirus receptor isoform 5 calculated_mol_wt: 36885 peptide sequence: LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV
 
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