MGP Database

MGP000739

Record overview

MGPD ID	MGP000739
Gene ID	1525
Species	Homo sapiens (Human)
Gene Name	coxsackie virus and adenovirus receptor
Gene Symbol	CXADR
Synonyms	CAR; HCAR; CAR4/6;
Alternate names	coxsackievirus and adenovirus receptor; 46 kD coxsackievirus and adenovirus receptor (CAR) protein; CVB3-binding protein; HCVADR; coxsackievirus B-adenovirus receptor;
Chromosome	21
Map Location	21q21.1
Summary	The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21. [provided by RefSeq, May 2011]
Orthologs	View orthologs and multiple alignments for CXADR

Proteins

coxsackievirus and adenovirus receptor isoform 1 precursor

Refseq ID:	NP_001329
Protein GI:	4503173
UniProt ID:	P78310
mRNA ID:	NM_001338
Length:	365
RefSeq Status:

`MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..252
product: coxsackievirus and adenovirus receptor isoform 2
calculated_mol_wt: 26148
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..365
product: Coxsackievirus and adenovirus receptor
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P78310.1)
calculated_mol_wt: 37978
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV

coxsackievirus and adenovirus receptor isoform 2 precursor

Refseq ID:	NP_001193992
Protein GI:	333470703
UniProt ID:	P78310
mRNA ID:	NM_001207063
Length:	252
RefSeq Status:

`MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAV RPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..252
product: coxsackievirus and adenovirus receptor isoform 2
calculated_mol_wt: 26148
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

coxsackievirus and adenovirus receptor isoform 3 precursor

Refseq ID:	NP_001193993
Protein GI:	333470707
UniProt ID:	P78310
mRNA ID:	NM_001207064
Length:	200
RefSeq Status:

`MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

coxsackievirus and adenovirus receptor isoform 4 precursor

Refseq ID:	NP_001193994
Protein GI:	333470705
UniProt ID:	P78310
mRNA ID:	NM_001207065
Length:	89
RefSeq Status:

`MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVGRCATSKEPYVHCQKLHRQ`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..252
product: coxsackievirus and adenovirus receptor isoform 2
calculated_mol_wt: 26148
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..365
product: Coxsackievirus and adenovirus receptor
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P78310.1)
calculated_mol_wt: 37978
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..352
product: coxsackievirus and adenovirus receptor isoform 5
calculated_mol_wt: 36885
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..89
product: coxsackievirus and adenovirus receptor isoform 4
calculated_mol_wt: 7914
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVGRCATSKEPYVHCQKLHRQ

coxsackievirus and adenovirus receptor isoform 5 precursor

Refseq ID:	NP_001193995
Protein GI:	333470709
UniProt ID:	P78310
mRNA ID:	NM_001207066
Length:	352
RefSeq Status:

`MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKS GDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVK NASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHS SLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV`

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..200
product: coxsackievirus and adenovirus receptor isoform 3
calculated_mol_wt: 20318
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLGKMCHLQRAVRPLPEATSAVIIHPWGPCLLPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..252
product: coxsackievirus and adenovirus receptor isoform 2
calculated_mol_wt: 26148
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAGKMCHLQRAVRPLPEATSAVIIHPWGPCL
LPTWKDIPRLSITKYQVKTLNALLRVRLSHLLR

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..365
product: Coxsackievirus and adenovirus receptor
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P78310.1)
calculated_mol_wt: 37978
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIPAQSKDGSIV

sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2071
peptide sequence: 
MALLLCFVLLCGVVDFARS

mat_peptide: 20..352
product: coxsackievirus and adenovirus receptor isoform 5
calculated_mol_wt: 36885
peptide sequence: 
LSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQ
CKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVG
SDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYN
QVPSEDFERTPQSPTLPPAKFKYPYKTDGITVV