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MGP000763

Record overview

MGPD IDMGP000763
Gene ID1579
SpeciesHomo sapiens (Human)
Gene Namecytochrome P450, family 4, subfamily A, polypeptide 11
Gene Symbol CYP4A11
SynonymsCP4Y; CYP4A2; CYP4AII;
Alternate namescytochrome P450 4A11; 20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; CYPIVA11; P450HL-omega; alkane-1 monooxygenase; cytochrome P-450HK-omega; cytochrome P450, subfamily IVA, polypeptide 11; cytochrome P450HL-omega; fatty acid omega-hydroxylase; lauric acid omega-hydroxylase;
Chromosome1
Map Location1p33
EC Number1.14.15.3
SummaryThis gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for CYP4A11

Proteins

cytochrome P450 4A11
Refseq ID:NP_000769
Protein GI:158937242
UniProt ID:Q02928
mRNA ID:NM_000778
Length:519
RefSeq Status:
MSVSVLSPSRLLGDVSGILQAASLLILLLLLIKAVQLYLHRQWLLKALQQFPCPPSHWLFGHIQELQQDQELQRIQKWVETFPSACPHWLWGGKVRVQLY
DPDYMKVILGRSDPKSHGSYRFLAPWIGYGLLLLNGQTWFQHRRMLTPAFHYDILKPYVGLMADSVRVMLDKWEELLGQDSPLEVFQHVSLMTLDTIMKC
AFSHQGSIQVDRNSQSYIQAISDLNNLVFSRVRNAFHQNDTIYSLTSAGRWTHRACQLAHQHTDQVIQLRKAQLQKEGELEKIKRKRHLDFLDILLLAKM
ENGSILSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLGDGASITWNHLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFP
DGRSLPKGIMVLLSIYGLHHNPKVWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIPIPIARLVLKSKN
GIHLRLRRLPNPCEDKDQL
 
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