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MGP000782

Record overview

MGPD IDMGP000782
Gene ID1606
SpeciesHomo sapiens (Human)
Gene Namediacylglycerol kinase, alpha 80kDa
Gene Symbol DGKA
SynonymsDAGK; DAGK1; DGK-alpha;
Alternate namesdiacylglycerol kinase alpha; 80 kDa diacylglycerol kinase; DAG kinase alpha; diglyceride kinase alpha;
Chromosome12
Map Location12q13.3
EC Number2.7.1.107
SummaryThe protein encoded by this gene belongs to the eukaryotic diacylglycerol kinase family. It acts as a modulator that competes with protein kinase C for the second messenger diacylglycerol in intracellular signaling pathways. It also plays an important role in the resynthesis of phosphatidylinositols and phosphorylating diacylglycerol to phosphatidic acid. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for DGKA

Proteins

diacylglycerol kinase alpha
Refseq ID:NP_001336
Protein GI:31542504
UniProt ID:P23743
mRNA ID:NM_001345
Length:735
RefSeq Status:
MAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVS
CYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTL
KDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHC
VWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYI
LNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRW
SVEVIPQQTEEKSDPVPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSNLSLEGIAVL
NIPSMHGGSNLWGDTRRPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGE
PWMQTPCTIKITHKNQMPMLMGPPPRSTNFFGFLS
 
diacylglycerol kinase alpha
Refseq ID:NP_963848
Protein GI:41872500
UniProt ID:P23743
mRNA ID:NM_201554
Length:735
RefSeq Status:
Protein sequence is identical to GI:31542504 (mRNA isoform)
 
diacylglycerol kinase alpha
Refseq ID:NP_958853
Protein GI:41872494
UniProt ID:P23743
mRNA ID:NM_201445
Length:735
RefSeq Status:
Protein sequence is identical to GI:31542504 (mRNA isoform)
 
diacylglycerol kinase alpha
Refseq ID:NP_958852
Protein GI:41393587
UniProt ID:P23743
mRNA ID:NM_201444
Length:735
RefSeq Status:
Protein sequence is identical to GI:31542504 (mRNA isoform)
 
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