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MGP000797

UniProt Annotations

Entry Information
Gene NamedCMP deaminase
Protein EntryDCTD_HUMAN
UniProt IDP32321
SpeciesHuman
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P32321-1; Sequence=Displayed; Name=2; IsoId=P32321-2; Sequence=VSP_038094;
Catalytic ActivitydCMP + H(2)O = dUMP + NH(3).
CofactorName=Zn(2+); Xref=ChEBI:CHEBI:29105;
Enzyme RegulationAllosteric enzyme whose activity is greatly influenced by the end products of its metabolic pathway, dCTP and dTTP.
FunctionSupplies the nucleotide substrate for thymidylate synthetase.
SimilarityBelongs to the cytidine and deoxycytidylate deaminase family. {ECO:0000305}.
SubunitHomohexamer. {ECO:0000269|Ref.8}.
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