MGP Database

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MGP000817

UniProt Annotations

Entry Information
Gene Namedefensin, alpha 6, Paneth cell-specific
Protein EntryDEF6_HUMAN
UniProt IDQ01524
SpeciesHuman
Comments
Comment typeDescription
FunctionHas very low antimicrobial activity against Gram- negative and Gram-positive bacteria. May protect cells against infection with HIV-1. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:17088326}.
SimilarityBelongs to the alpha-defensin family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitHomodimer. {ECO:0000269|PubMed:17088326}.
Tissue SpecificityPaneth cells of the small intestine.
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