MGP Database

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MGP000866

Ontology/Pathway Information

Entrez Gene ID1807
Gene Namedihydropyrimidinase
Gene Symbol DPYS
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 ISS:UniProtKBCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0016597 IEA:EnsemblFamino acid binding
GO:0004157 IDA:UniProtKBFdihydropyrimidinase activity
GO:0002059 IEA:EnsemblFthymine binding
GO:0002058 IEA:EnsemblFuracil binding
GO:0008270 NAS:UniProtKBFzinc ion binding
GO:0019482 IEA:EnsemblPbeta-alanine metabolic process
GO:0055086 TAS:ReactomePnucleobase-containing small molecule metabolic process
GO:0051289 ISS:UniProtKBPprotein homotetramerization
GO:0006208 IDA:UniProtKBPpyrimidine nucleobase catabolic process
GO:0006206 TAS:ReactomePpyrimidine nucleobase metabolic process
GO:0046135 TAS:ReactomePpyrimidine nucleoside catabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006210 ISS:UniProtKBPthymine catabolic process
GO:0006212 IDA:UniProtKBPuracil catabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111217Metabolism
REACT_1698Metabolism of nucleotides
REACT_1023Pyrimidine catabolism
REACT_957Pyrimidine metabolism
SMP Pathway Links
SMP IDDescription
SMP00007Beta-Alanine Metabolism
SMP00172Beta Ureidopropionase Deficiency
SMP00493Carnosinuria, carnosinemia
SMP00178Dihydropyrimidinase Deficiency
SMP00351GABA-Transaminase Deficiency
SMP00202MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
SMP00046Pyrimidine Metabolism
SMP00219UMP Synthase Deiciency (Orotic Aciduria)
SMP00492Ureidopropionase deficiency
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