MGP Database

MGP000935

Ontology/Pathway Information

Entrez Gene ID1968
Gene Nameeukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
Gene Symbol EIF2S3
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0003924 TAS:ProtIncFGTPase activity
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0008135 IDA:UniProtKBFtranslation factor activity, nucleic acid binding
GO:0003743 IDA:UniProtKBFtranslation initiation factor activity
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0010467 TAS:ReactomePgene expression
GO:0006184 TAS:GOCPGTP catabolic process
GO:0006412 TAS:ReactomePtranslation
GO:0006413 IDA:UniProtKBPtranslational initiation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1258Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
REACT_2099Cap-dependent Translation Initiation
REACT_2159Eukaryotic Translation Initiation
REACT_1079Formation of the ternary complex, and subsequently, the 43S complex
REACT_71Gene Expression
REACT_2085GTP hydrolysis and joining of the 60S ribosomal subunit
REACT_79L13a-mediated translational silencing of Ceruloplasmin expression
REACT_17015Metabolism of proteins
REACT_1815Recycling of eIF2:GDP
REACT_931Ribosomal scanning and start codon recognition
REACT_1014Translation
REACT_1979Translation initiation complex formation
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