MGP Database

MGP000944

Record overview

MGPD IDMGP000944
Gene ID1983
SpeciesHomo sapiens (Human)
Gene Nameeukaryotic translation initiation factor 5
Gene Symbol EIF5
SynonymsEIF-5; EIF-5A;
Alternate nameseukaryotic translation initiation factor 5;
Chromosome14
Map Location14q32.32
SummaryEukaryotic translation initiation factor-5 (EIF5) interacts with the 40S initiation complex to promote hydrolysis of bound GTP with concomitant joining of the 60S ribosomal subunit to the 40S initiation complex. The resulting functional 80S ribosomal initiation complex is then active in peptidyl transfer and chain elongations (summary by Si et al., 1996 [PubMed 8663286]).[supplied by OMIM, May 2010]
OrthologsView orthologs and multiple alignments for EIF5

Proteins

eukaryotic translation initiation factor 5
Refseq ID:NP_001960
Protein GI:21361337
UniProt ID:P55010
mRNA ID:NM_001969
Length:431
RefSeq Status:
MSVNVNRSVSDQFYRYKMPRLIAKVEGKGNGIKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDVKNDRYIVNGSHEANKLQDMLDGFIKKFVLCP
ECENPETDLHVNPKKQTIGNSCKACGYRGMLDTHHKLCTFILKNPPENSDSGTGKKEKEKKNRKGKDKENGSVSSSETPPPPPPPNEINPPPHTMEEEED
DDWGEDTTEEAQRRRMDEISDHAKVLTLSDDLERTIEERVNILFDFVKKKKEEGVIDSSDKEIVAEAERLDVKAMGPLVLTEVLFNEKIREQIKKYRRHF
LRFCHNNKKAQRYLLHGLECVVAMHQAQLISKIPHILKEMYDADLLEEEVIISWSEKASKKYVSKELAKEIRVKAEPFIKWLKEAEEESSGGEEEDEDEN
IEVVYSKAASVPKVETVKSDNKDDDIDIDAI
 
eukaryotic translation initiation factor 5
Refseq ID:NP_892116
Protein GI:37537716
UniProt ID:P55010
mRNA ID:NM_183004
Length:431
RefSeq Status:
Protein sequence is identical to GI:21361337 (mRNA isoform)
 
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