MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP000944

UniProt Annotations

Entry Information
Gene Nameeukaryotic translation initiation factor 5
Protein EntryIF5_HUMAN
UniProt IDP55010
SpeciesHuman
Comments
Comment typeDescription
FunctionCatalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
SimilarityBelongs to the eIF-2-beta/eIF-5 family. {ECO:0000305}.
SimilarityContains 1 W2 domain. {ECO:0000255|PROSITE- ProRule:PRU00695}.
  logo