MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001006

Ontology/Pathway Information

Entrez Gene ID2150
Gene Namecoagulation factor II (thrombin) receptor-like 1
Gene Symbol F2RL1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005769 IDA:UniProtKBCearly endosome
GO:0005794 TAS:ProtIncCGolgi apparatus
GO:0005887 IDA:BHF-UCLCintegral component of plasma membrane
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0031143 ISS:UniProtKBCpseudopodium
GO:0001965 ISS:UniProtKBFG-protein alpha-subunit binding
GO:0031681 ISS:UniProtKBFG-protein beta-subunit binding
GO:0004930 IMP:UniProtKBFG-protein coupled receptor activity
GO:0004872 TAS:ProtIncFreceptor activity
GO:0005102 TAS:ProtIncFreceptor binding
GO:0015057 IEA:InterProFthrombin receptor activity
GO:0007596 IEA:InterProPblood coagulation
GO:0035926 IDA:UniProtKBPchemokine (C-C motif) ligand 2 secretion
GO:0090195 IDA:UniProtKBPchemokine secretion
GO:0051607 IDA:UniProtKBPdefense response to virus
GO:0061028 IDA:UniProtKBPestablishment of endothelial barrier
GO:0007186 TAS:ProtIncPG-protein coupled receptor signaling pathway
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 IEA:UniProtKB-KWPinnate immune response
GO:0072643 ISS:UniProtKBPinterferon-gamma secretion
GO:0072608 IDA:UniProtKBPinterleukin-10 secretion
GO:0050702 IDA:UniProtKBPinterleukin-1 beta secretion
GO:0050900 IDA:UniProtKBPleukocyte migration
GO:0070661 ISS:UniProtKBPleukocyte proliferation
GO:0097029 IDA:UniProtKBPmature conventional dendritic cell differentiation
GO:0090198 IDA:UniProtKBPnegative regulation of chemokine secretion
GO:0046329 IDA:UniProtKBPnegative regulation of JNK cascade
GO:0034140 IMP:UniProtKBPnegative regulation of toll-like receptor 3 signaling pathway
GO:0010804 IDA:UniProtKBPnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0042119 IDA:UniProtKBPneutrophil activation
GO:0030836 IDA:UniProtKBPpositive regulation of actin filament depolymerization
GO:0030335 ISS:UniProtKBPpositive regulation of cell migration
GO:0050921 ISS:UniProtKBPpositive regulation of chemotaxis
GO:0002741 IDA:UniProtKBPpositive regulation of cytokine secretion involved in immune response
GO:0007204 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0043311 IDA:UniProtKBPpositive regulation of eosinophil degranulation
GO:0070374 IDA:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0003104 ISS:UniProtKBPpositive regulation of glomerular filtration
GO:0043123 IDA:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:2000778 IDA:UniProtKBPpositive regulation of interleukin-6 secretion
GO:2000484 IDA:UniProtKBPpositive regulation of interleukin-8 secretion
GO:0046330 IDA:UniProtKBPpositive regulation of JNK cascade
GO:0002690 IDA:BHF-UCLPpositive regulation of leukocyte chemotaxis
GO:0070963 IDA:UniProtKBPpositive regulation of neutrophil mediated killing of gram-negative bacterium
GO:0060100 IDA:UniProtKBPpositive regulation of phagocytosis, engulfment
GO:0014068 ISS:UniProtKBPpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0050927 IDA:BHF-UCLPpositive regulation of positive chemotaxis
GO:0031274 ISS:UniProtKBPpositive regulation of pseudopodium assembly
GO:1900135 ISS:UniProtKBPpositive regulation of renin secretion into blood stream
GO:0035025 IMP:UniProtKBPpositive regulation of Rho protein signal transduction
GO:0032930 IDA:UniProtKBPpositive regulation of superoxide anion generation
GO:0034137 IMP:UniProtKBPpositive regulation of toll-like receptor 2 signaling pathway
GO:0034141 IMP:UniProtKBPpositive regulation of toll-like receptor 3 signaling pathway
GO:0034145 IDA:UniProtKBPpositive regulation of toll-like receptor 4 signaling pathway
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0045909 ISS:UniProtKBPpositive regulation of vasodilation
GO:0030193 IDA:BHF-UCLPregulation of blood coagulation
GO:0043122 IDA:UniProtKBPregulation of I-kappaB kinase/NF-kappaB signaling
GO:0046328 IDA:UniProtKBPregulation of JNK cascade
GO:0002286 ISS:UniProtKBPT cell activation involved in immune response
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_14828Class A/1 (Rhodopsin-like receptors)
REACT_267874Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125Disease
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_21340GPCR ligand binding
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_14819Peptide ligand-binding receptors
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
  logo