MGP Database

MGP001048

Record overview

MGPD ID	MGP001048
Gene ID	2212
Species	Homo sapiens (Human)
Gene Name	Fc fragment of IgG, low affinity IIa, receptor (CD32)
Gene Symbol	FCGR2A
Synonyms	CD32; FCG2; FcGR; CD32A; CDw32; FCGR2; IGFR2; FCGR2A1;
Alternate names	low affinity immunoglobulin gamma Fc region receptor II-a; Immunoglobulin G Fc receptor II; fc-gamma RII-a; fc-gamma-RIIa; fcRII-a; igG Fc receptor II-a;
Chromosome	1
Map Location	1q23
Summary	This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]
Orthologs	View orthologs and multiple alignments for FCGR2A

Proteins

low affinity immunoglobulin gamma Fc region receptor II-a isoform 1 precursor

Refseq ID:	NP_001129691
Protein GI:	210031822
UniProt ID:	P12318
mRNA ID:	NM_001136219
Length:	317
RefSeq Status:

`MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSG EYTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKP VTITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDD KNIYLTLPPNDHVNSNN`

low affinity immunoglobulin gamma Fc region receptor II-a isoform 2 precursor
`sig_peptide: 1..33 inference: COORDINATES: ab initio prediction:SignalP:4.0 calculated_mol_wt: 3718 peptide sequence: MTMETQMSQNVCPRNLWLLQPLTVLLLLASADS`

Refseq ID:	NP_067674
Protein GI:	50511936
UniProt ID:	P12318
mRNA ID:	NM_021642
Length:	316
RefSeq Status:

`MTMETQMSQNVCPRNLWLLQPLTVLLLLASADSQAAPPKAVLKLEPPWINVLQEDSVTLTCQGARSPESDSIQWFHNGNLIPTHTQPSYRFKANNNDSGE YTCQTGQTSLSDPVHLTVLSEWLVLQTPHLEFQEGETIMLRCHSWKDKPLVKVTFFQNGKSQKFSHLDPTFSIPQANHSHSGDYHCTGNIGYTLFSSKPV TITVQVPSMGSSSPMGIIVAVVIATAVAAIVAAVVALIYCRKKRISANSTDPVKAAQFEPPGRQMIAIRKRQLEETNNDYETADGGYMTLNPRAPTDDDK NIYLTLPPNDHVNSNN`

sig_peptide: 1..33
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3718
peptide sequence: 
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADS

sig_peptide: 1..33
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 3718
peptide sequence: 
MTMETQMSQNVCPRNLWLLQPLTVLLLLASADS