MGP Database

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MGP001051

Ontology/Pathway Information

Entrez Gene ID2219
Gene Nameficolin (collagen/fibrinogen domain containing) 1
Gene Symbol FCN1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005581 IEA:UniProtKB-KWCcollagen trimer
GO:0005576 TAS:ReactomeCextracellular region
GO:0031232 IDA:UniProtKBCextrinsic component of external side of plasma membrane
GO:0003823 TAS:ProtIncFantigen binding
GO:0005509 TAS:ProtIncFcalcium ion binding
GO:0030246 TAS:ProtIncFcarbohydrate binding
GO:0001664 IPI:UniProtKBFG-protein coupled receptor binding
GO:0008329 IMP:UniProtKBFsignaling pattern recognition receptor activity
GO:0002752 IMP:UniProtKBPcell surface pattern recognition receptor signaling pathway
GO:0006956 TAS:ReactomePcomplement activation
GO:0001867 TAS:ReactomePcomplement activation, lectin pathway
GO:0007186 IDA:UniProtKBPG-protein coupled receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0008228 TAS:ProtIncPopsonization
GO:2000484 IMP:UniProtKBPpositive regulation of interleukin-8 secretion
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6932Complement cascade
REACT_8012Creation of C4 and C2 activators
REACT_163810Ficolins bind to repetitive carbohydrate structures on the target cell surface
REACT_6900Immune System
REACT_8024Initial triggering of complement
REACT_6802Innate Immune System
REACT_7964Lectin pathway of complement activation
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