MGP Database

MGP001071

Ontology/Pathway Information

Entrez Gene ID	2254
Gene Name	fibroblast growth factor 9
Gene Symbol	FGF9
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005604	IEA:Ensembl	C	basement membrane
GO:0005737	IEA:Ensembl	C	cytoplasm
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IDA:MGI	C	extracellular space
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0008083	TAS:ProtInc	F	growth factor activity
GO:0008201	IEA:UniProtKB-KW	F	heparin binding
GO:0001525	IEA:Ensembl	P	angiogenesis
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0002062	IEA:Ensembl	P	chondrocyte differentiation
GO:0048566	IEA:Ensembl	P	embryonic digestive tract development
GO:0030326	IEA:Ensembl	P	embryonic limb morphogenesis
GO:0048706	IEA:Ensembl	P	embryonic skeletal system development
GO:0007173	TAS:Reactome	P	epidermal growth factor receptor signaling pathway
GO:0038095	TAS:Reactome	P	Fc-epsilon receptor signaling pathway
GO:0008543	IGI:MGI	P	fibroblast growth factor receptor signaling pathway
GO:0045087	TAS:Reactome	P	innate immune response
GO:0042472	IEA:Ensembl	P	inner ear morphogenesis
GO:0008286	TAS:Reactome	P	insulin receptor signaling pathway
GO:0060484	IEA:Ensembl	P	lung-associated mesenchyme development
GO:0008584	IEP:UniProtKB	P	male gonad development
GO:0030238	IEA:Ensembl	P	male sex determination
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0030178	IEA:Ensembl	P	negative regulation of Wnt signaling pathway
GO:0048011	TAS:Reactome	P	neurotrophin TRK receptor signaling pathway
GO:0001649	IEA:Ensembl	P	osteoblast differentiation
GO:0048015	TAS:Reactome	P	phosphatidylinositol-mediated signaling
GO:0090263	IEA:Ensembl	P	positive regulation of canonical Wnt signaling pathway
GO:0060045	IEA:Ensembl	P	positive regulation of cardiac muscle cell proliferation
GO:0051781	IEA:UniProtKB-KW	P	positive regulation of cell division
GO:0008284	IDA:MGI	P	positive regulation of cell proliferation
GO:0050679	IEA:Ensembl	P	positive regulation of epithelial cell proliferation
GO:0010628	IEA:Ensembl	P	positive regulation of gene expression
GO:0043410	IEA:Ensembl	P	positive regulation of MAPK cascade
GO:0002053	IEA:Ensembl	P	positive regulation of mesenchymal cell proliferation
GO:0045880	IEA:Ensembl	P	positive regulation of smoothened signaling pathway
GO:0030949	IEA:Ensembl	P	positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0006606	IEA:Ensembl	P	protein import into nucleus
GO:0048505	IEA:Ensembl	P	regulation of timing of cell differentiation
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0021762	IEP:UniProtKB	P	substantia nigra development

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_120863	Activated point mutants of FGFR2
REACT_75774	Adaptive Immune System
REACT_147727	Constitutive PI3K/AKT Signaling in Cancer
REACT_147694	DAP12 interactions
REACT_147814	DAP12 signaling
REACT_116125	Disease
REACT_118638	Downstream signaling events of B Cell Receptor (BCR)
REACT_21272	Downstream signaling of activated FGFR
REACT_17025	Downstream signal transduction
REACT_163936	Fc epsilon receptor (FCERI) signaling
REACT_9515	FGFR1c ligand binding and activation
REACT_9483	FGFR1 ligand binding and activation
REACT_9413	FGFR2c ligand binding and activation
REACT_9390	FGFR2 ligand binding and activation
REACT_9508	FGFR3b ligand binding and activation
REACT_9510	FGFR3c ligand binding and activation
REACT_9439	FGFR3 ligand binding and activation
REACT_9452	FGFR4 ligand binding and activation
REACT_9396	FGFR ligand binding and activation
REACT_21247	FRS2-mediated cascade
REACT_12578	GAB1 signalosome
REACT_150210	IGF1R signaling cascade
REACT_6900	Immune System
REACT_6802	Innate Immune System
REACT_1195	Insulin receptor signalling cascade
REACT_332	IRS-mediated signalling
REACT_762	IRS-related events
REACT_150203	IRS-related events triggered by IGF1R
REACT_111184	Negative regulation of FGFR signaling
REACT_12056	NGF signalling via TRKA from the plasma membrane
REACT_21310	Phospholipase C-mediated cascade
REACT_12464	PI3K/AKT activation
REACT_147723	PI3K/AKT Signaling in Cancer
REACT_21270	PI-3K cascade
REACT_976	PI3K Cascade
REACT_116008	PI3K events in ERBB2 signaling
REACT_115961	PI3K events in ERBB4 signaling
REACT_75829	PIP3 activates AKT signaling
REACT_163769	Role of LAT2/NTAL/LAB on calcium mobilization
REACT_21374	SHC-mediated cascade
REACT_121153	Signaling by activated point mutants of FGFR1
REACT_121337	Signaling by activated point mutants of FGFR3
REACT_9417	Signaling by EGFR
REACT_115871	Signaling by EGFR in Cancer
REACT_268269	Signaling by EGFRvIII in Cancer
REACT_115755	Signaling by ERBB2
REACT_115596	Signaling by ERBB4
REACT_9470	Signaling by FGFR
REACT_120999	Signaling by FGFR1 mutants
REACT_121155	Signaling by FGFR2 mutants
REACT_121249	Signaling by FGFR3 mutants
REACT_120736	Signaling by FGFR in disease
REACT_121398	Signaling by FGFR mutants
REACT_498	Signaling by Insulin receptor
REACT_268006	Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546	Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888	Signaling by PDGF
REACT_111040	Signaling by SCF-KIT
REACT_118773	Signaling by the B Cell Receptor (BCR)
REACT_150359	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_11061	Signalling by NGF
REACT_111102	Signal Transduction