MGP Database

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MGP001079

Ontology/Pathway Information

Entrez Gene ID2268
Gene NameFGR proto-oncogene, Src family tyrosine kinase
Gene Symbol FGR
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0015629 IEA:EnsemblCactin cytoskeleton
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0031234 IBA:GO_CentralCextrinsic component of cytoplasmic side of plasma membrane
GO:0005743 IEA:UniProtKB-SubCellCmitochondrial inner membrane
GO:0005758 IEA:UniProtKB-SubCellCmitochondrial intermembrane space
GO:0005886 ISS:UniProtKBCplasma membrane
GO:0032587 IEA:UniProtKB-SubCellCruffle membrane
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0034988 IDA:UniProtKBFFc-gamma receptor I complex binding
GO:0034987 ISS:UniProtKBFimmunoglobulin receptor binding
GO:0004715 IDA:UniProtKBFnon-membrane spanning protein tyrosine kinase activity
GO:0001784 ISS:UniProtKBFphosphotyrosine binding
GO:0019901 ISS:UniProtKBFprotein kinase binding
GO:0004713 IDA:UniProtKBFprotein tyrosine kinase activity
GO:0007596 TAS:ReactomePblood coagulation
GO:0030154 IBA:GO_CentralPcell differentiation
GO:0016477 IBA:GO_CentralPcell migration
GO:0071375 IBA:GO_CentralPcellular response to peptide hormone stimulus
GO:0050830 ISS:UniProtKBPdefense response to Gram-positive bacterium
GO:0038096 TAS:ReactomePFc-gamma receptor signaling pathway involved in phagocytosis
GO:0002768 TAS:UniProtKBPimmune response-regulating cell surface receptor signaling pathway
GO:0045087 IBA:GO_CentralPinnate immune response
GO:0007229 IMP:UniProtKBPintegrin-mediated signaling pathway
GO:0038083 IBA:GO_CentralPpeptidyl-tyrosine autophosphorylation
GO:0018108 IDA:UniProtKBPpeptidyl-tyrosine phosphorylation
GO:0030335 ISS:UniProtKBPpositive regulation of cell migration
GO:0050715 ISS:UniProtKBPpositive regulation of cytokine secretion
GO:0043306 ISS:UniProtKBPpositive regulation of mast cell degranulation
GO:0043552 IMP:UniProtKBPpositive regulation of phosphatidylinositol 3-kinase activity
GO:0014068 IMP:UniProtKBPpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0046777 IDA:UniProtKBPprotein autophosphorylation
GO:0006468 TAS:ProtIncPprotein phosphorylation
GO:0042127 IBA:GO_CentralPregulation of cell proliferation
GO:0008360 ISS:UniProtKBPregulation of cell shape
GO:0045088 ISS:UniProtKBPregulation of innate immune response
GO:0050764 ISS:UniProtKBPregulation of phagocytosis
GO:0045859 ISS:UniProtKBPregulation of protein kinase activity
GO:0009615 TAS:ProtIncPresponse to virus
GO:0007169 IBA:GO_CentralPtransmembrane receptor protein tyrosine kinase signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_160123Fcgamma receptor (FCGR) dependent phagocytosis
REACT_160274FCGR activation
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_23876Platelet homeostasis
REACT_23879Platelet sensitization by LDL
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