MGP Database

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MGP001086

Ontology/Pathway Information

Entrez Gene ID2305
Gene Nameforkhead box M1
Gene Symbol FOXM1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0005654 IDA:HPACnucleoplasm
GO:0003677 IDA:UniProtKBFDNA binding
GO:0019901 IPI:UniProtKBFprotein kinase binding
GO:0043565 IEA:InterProFsequence-specific DNA binding
GO:0000981 IBA:GO_CentralFsequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003700 IDA:UniProtKBFsequence-specific DNA binding transcription factor activity
GO:0044212 IEA:EnsemblFtranscription regulatory region DNA binding
GO:0007049 TAS:UniProtKBPcell cycle
GO:0006978 IMP:UniProtKBPDNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006281 IEA:UniProtKB-KWPDNA repair
GO:0000086 IDA:UniProtKBPG2/M transition of mitotic cell cycle
GO:0001889 IEA:EnsemblPliver development
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0090344 IMP:UniProtKBPnegative regulation of cell aging
GO:0032873 IMP:BHF-UCLPnegative regulation of stress-activated MAPK cascade
GO:0045892 IMP:BHF-UCLPnegative regulation of transcription, DNA-templated
GO:0000122 IMP:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0008284 IMP:BHF-UCLPpositive regulation of cell proliferation
GO:2000781 IMP:UniProtKBPpositive regulation of double-strand break repair
GO:0045893 IMP:UniProtKBPpositive regulation of transcription, DNA-templated
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0051726 TAS:ReactomePregulation of cell cycle
GO:0071156 IMP:BHF-UCLPregulation of cell cycle arrest
GO:0001558 TAS:UniProtKBPregulation of cell growth
GO:0042127 NAS:UniProtKBPregulation of cell proliferation
GO:0046578 IMP:BHF-UCLPregulation of Ras protein signal transduction
GO:2000377 IMP:BHF-UCLPregulation of reactive oxygen species metabolic process
GO:0006355 IDA:GOCPregulation of transcription, DNA-templated
GO:0006366 IDA:UniProtKBPtranscription from RNA polymerase II promoter
GO:0001570 IEA:EnsemblPvasculogenesis
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_115566Cell Cycle
REACT_152Cell Cycle, Mitotic
REACT_1857Cyclin A/B1 associated events during G2/M transition
REACT_2203G2/M Transition
REACT_21391Mitotic G2-G2/M phases
REACT_1006Polo-like kinase mediated events
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