MGP Database

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MGP001160

Ontology/Pathway Information

Entrez Gene ID2621
Gene Namegrowth arrest-specific 6
Gene Symbol GAS6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005788 TAS:ReactomeCendoplasmic reticulum lumen
GO:0005576 TAS:ReactomeCextracellular region
GO:0005615 IDA:UniProtKBCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005796 TAS:ReactomeCGolgi lumen
GO:0031093 TAS:ReactomeCplatelet alpha granule lumen
GO:0060090 IDA:UniProtKBFbinding, bridging
GO:0005509 IEA:InterProFcalcium ion binding
GO:0043027 IDA:UniProtKBFcysteine-type endopeptidase inhibitor activity involved in apoptotic process
GO:0001786 IDA:UniProtKBFphosphatidylserine binding
GO:0030296 IDA:UniProtKBFprotein tyrosine kinase activator activity
GO:0048018 IDA:MGIFreceptor agonist activity
GO:0005102 IDA:UniProtKBFreceptor binding
GO:0030971 IPI:UniProtKBFreceptor tyrosine kinase binding
GO:0005245 IDA:UniProtKBFvoltage-gated calcium channel activity
GO:0032148 ISS:UniProtKBPactivation of protein kinase B activity
GO:0043277 IDA:UniProtKBPapoptotic cell clearance
GO:0035754 IDA:UniProtKBPB cell chemotaxis
GO:0007596 TAS:ReactomePblood coagulation
GO:0070588 IDA:UniProtKBPcalcium ion transmembrane transport
GO:0007155 TAS:UniProtKBPcell adhesion
GO:0007050 TAS:UniProtKBPcell cycle arrest
GO:0016477 TAS:UniProtKBPcell migration
GO:0008283 TAS:UniProtKBPcell proliferation
GO:0031589 IEA:EnsemblPcell-substrate adhesion
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0035690 IDA:UniProtKBPcellular response to drug
GO:0071333 ISS:UniProtKBPcellular response to glucose stimulus
GO:0071363 IEA:EnsemblPcellular response to growth factor stimulus
GO:0035457 IDA:UniProtKBPcellular response to interferon-alpha
GO:0009267 IEA:EnsemblPcellular response to starvation
GO:0071307 IDA:UniProtKBPcellular response to vitamin K
GO:0097028 IEP:UniProtKBPdendritic cell differentiation
GO:0007167 IEA:EnsemblPenzyme linked receptor protein signaling pathway
GO:0085029 ISS:UniProtKBPextracellular matrix assembly
GO:0019064 IDA:UniProtKBPfusion of virus membrane with host plasma membrane
GO:0097241 IDA:UniProtKBPhematopoietic stem cell migration to bone marrow
GO:0050900 TAS:ReactomePleukocyte migration
GO:0010934 IEA:EnsemblPmacrophage cytokine production
GO:0043066 IDA:UniProtKBPnegative regulation of apoptotic process
GO:0070168 IDA:UniProtKBPnegative regulation of biomineral tissue development
GO:0043154 IDA:UniProtKBPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2000669 IDA:UniProtKBPnegative regulation of dendritic cell apoptotic process
GO:2000352 IDA:UniProtKBPnegative regulation of endothelial cell apoptotic process
GO:2000270 IDA:UniProtKBPnegative regulation of fibroblast apoptotic process
GO:0032689 IDA:UniProtKBPnegative regulation of interferon-gamma production
GO:0050711 IDA:UniProtKBPnegative regulation of interleukin-1 secretion
GO:0032715 IDA:UniProtKBPnegative regulation of interleukin-6 production
GO:1900165 IDA:UniProtKBPnegative regulation of interleukin-6 secretion
GO:1900142 IDA:UniProtKBPnegative regulation of oligodendrocyte apoptotic process
GO:0033159 IDA:UniProtKBPnegative regulation of protein import into nucleus, translocation
GO:2000533 ISS:UniProtKBPnegative regulation of renal albumin absorption
GO:0043433 IDA:UniProtKBPnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892 IDA:UniProtKBPnegative regulation of transcription, DNA-templated
GO:0010804 IDA:UniProtKBPnegative regulation of tumor necrosis factor-mediated signaling pathway
GO:0032720 IDA:UniProtKBPnegative regulation of tumor necrosis factor production
GO:0001764 IEA:EnsemblPneuron migration
GO:0031100 IEA:EnsemblPorgan regeneration
GO:0017187 TAS:ReactomePpeptidyl-glutamic acid carboxylation
GO:0018105 IDA:UniProtKBPpeptidyl-serine phosphorylation
GO:0006909 IDA:UniProtKBPphagocytosis
GO:0030168 TAS:UniProtKBPplatelet activation
GO:0070527 TAS:UniProtKBPplatelet aggregation
GO:0002576 TAS:ReactomePplatelet degranulation
GO:0001961 IMP:UniProtKBPpositive regulation of cytokine-mediated signaling pathway
GO:2000510 IDA:UniProtKBPpositive regulation of dendritic cell chemotaxis
GO:0070374 IDA:MGIPpositive regulation of ERK1 and ERK2 cascade
GO:0048146 IDA:UniProtKBPpositive regulation of fibroblast proliferation
GO:0010628 IDA:UniProtKBPpositive regulation of gene expression
GO:0003104 ISS:UniProtKBPpositive regulation of glomerular filtration
GO:0032825 IDA:UniProtKBPpositive regulation of natural killer cell differentiation
GO:0033138 IDA:UniProtKBPpositive regulation of peptidyl-serine phosphorylation
GO:0050766 IDA:UniProtKBPpositive regulation of phagocytosis
GO:0046827 IDA:UniProtKBPpositive regulation of protein export from nucleus
GO:0045860 IDA:UniProtKBPpositive regulation of protein kinase activity
GO:0051897 IDA:UniProtKBPpositive regulation of protein kinase B signaling
GO:0001934 IDA:UniProtKBPpositive regulation of protein phosphorylation
GO:0061098 IDA:UniProtKBPpositive regulation of protein tyrosine kinase activity
GO:0032008 ISS:UniProtKBPpositive regulation of TOR signaling
GO:0043687 TAS:ReactomePpost-translational protein modification
GO:0043491 IDA:UniProtKBPprotein kinase B signaling
GO:0006468 IDA:UniProtKBPprotein phosphorylation
GO:0072661 IDA:UniProtKBPprotein targeting to plasma membrane
GO:0006508 TAS:ReactomePproteolysis
GO:0046813 IDA:UniProtKBPreceptor-mediated virion attachment to host cell
GO:0040008 IEA:UniProtKB-KWPregulation of growth
GO:0007165 IDA:UniProtKBPsignal transduction
GO:0046718 IDA:UniProtKBPviral entry into host cell
GO:0019079 IDA:UniProtKBPviral genome replication
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_12051Cell surface interactions at the vascular wall
REACT_1069Gamma carboxylation, hypusine formation and arylsulfatase activation
REACT_1050Gamma-carboxylation of protein precursors
REACT_1132Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
REACT_604Hemostasis
REACT_17015Metabolism of proteins
REACT_798Platelet activation, signaling and aggregation
REACT_318Platelet degranulation
REACT_22161Post-translational protein modification
REACT_733Removal of aminoterminal propeptides from gamma-carboxylated proteins
REACT_1280Response to elevated platelet cytosolic Ca2+
REACT_1906Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus
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