MGP Database

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MGP001162

Record overview

MGPD IDMGP001162
Gene ID2624
SpeciesHomo sapiens (Human)
Gene NameGATA binding protein 2
Gene Symbol GATA2
SynonymsDCML; IMD21; NFE1B; MONOMAC;
Alternate namesendothelial transcription factor GATA-2;
Chromosome3
Map Location3q21.3
SummaryThis gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
OrthologsView orthologs and multiple alignments for GATA2

Proteins

endothelial transcription factor GATA-2 isoform 1
Refseq ID:NP_116027
Protein GI:20070352
UniProt ID:P23769
mRNA ID:NM_032638
Length:480
RefSeq Status:
MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDG
GKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGG
SAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKM
SNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
 
endothelial transcription factor GATA-2 isoform 1
Refseq ID:NP_001139133
Protein GI:224611699
UniProt ID:P23769
mRNA ID:NM_001145661
Length:480
RefSeq Status:
Protein sequence is identical to GI:20070352 (mRNA isoform)
 
endothelial transcription factor GATA-2 isoform 2
Refseq ID:NP_001139134
Protein GI:224611701
UniProt ID:P23769
mRNA ID:NM_001145662
Length:466
RefSeq Status:
MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDG
GKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGG
SAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGA
TATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECF
EELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG
 
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