MGP Database

MGP001162

Ontology/Pathway Information

Entrez Gene ID	2624
Gene Name	GATA binding protein 2
Gene Symbol	GATA2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005654	IDA:HPA	C	nucleoplasm
GO:0043234	IEA:Ensembl	C	protein complex
GO:0070742	IPI:BHF-UCL	F	C2H2 zinc finger domain binding
GO:0003682	IDA:MGI	F	chromatin binding
GO:0001158	IDA:MGI	F	enhancer sequence-specific DNA binding
GO:0001077	IEA:Ensembl	F	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0000980	IEA:Ensembl	F	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003700	IDA:UniProtKB	F	sequence-specific DNA binding transcription factor activity
GO:0008134	IPI:BHF-UCL	F	transcription factor binding
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0021533	IEA:Ensembl	P	cell differentiation in hindbrain
GO:0001709	IEA:Ensembl	P	cell fate determination
GO:0048469	IEA:Ensembl	P	cell maturation
GO:0021954	IEA:Ensembl	P	central nervous system neuron development
GO:0021902	IEA:Ensembl	P	commitment of neuronal cell to specific neuron type in forebrain
GO:0060216	IEA:Ensembl	P	definitive hemopoiesis
GO:0001892	IEA:Ensembl	P	embryonic placenta development
GO:0035854	IDA:BHF-UCL	P	eosinophil fate commitment
GO:0097154	IEA:Ensembl	P	GABAergic neuron differentiation
GO:0048873	IEA:Ensembl	P	homeostasis of number of cells within a tissue
GO:0042472	IEA:Ensembl	P	inner ear morphogenesis
GO:0045599	IMP:UniProtKB	P	negative regulation of fat cell differentiation
GO:0070345	IMP:UniProtKB	P	negative regulation of fat cell proliferation
GO:0045650	IEA:Ensembl	P	negative regulation of macrophage differentiation
GO:2000178	IDA:MGI	P	negative regulation of neural precursor cell proliferation
GO:0045746	IDA:MGI	P	negative regulation of Notch signaling pathway
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0006909	IEA:UniProtKB-KW	P	phagocytosis
GO:0021983	IEA:Ensembl	P	pituitary gland development
GO:0045766	IDA:MGI	P	positive regulation of angiogenesis
GO:0045648	IEA:Ensembl	P	positive regulation of erythrocyte differentiation
GO:0045654	IEA:Ensembl	P	positive regulation of megakaryocyte differentiation
GO:0050766	ISS:UniProtKB	P	positive regulation of phagocytosis
GO:0045944	IDA:UniProtKB	P	positive regulation of transcription from RNA polymerase II promoter
GO:2000977	IEA:Ensembl	P	regulation of forebrain neuron differentiation
GO:0035065	IEA:Ensembl	P	regulation of histone acetylation
GO:0060872	IEA:Ensembl	P	semicircular canal development
GO:0035019	IEA:Ensembl	P	somatic stem cell maintenance
GO:0006351	IDA:UniProtKB	P	transcription, DNA-templated
GO:0001655	IEA:Ensembl	P	urogenital system development
GO:0021514	IEA:Ensembl	P	ventral spinal cord interneuron differentiation

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_24970	Factors involved in megakaryocyte development and platelet production
REACT_604	Hemostasis