MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP001198

Ontology/Pathway Information

Entrez Gene ID2687
Gene Namegamma-glutamyltransferase 5
Gene Symbol GGT5
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0031362 TAS:UniProtKBCanchored component of external side of plasma membrane
GO:0016021 TAS:ProtIncCintegral component of membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0003840 TAS:UniProtKBFgamma-glutamyltransferase activity
GO:0036374 IEA:UniProtKB-ECFglutathione hydrolase activity
GO:0019369 TAS:ReactomeParachidonic acid metabolic process
GO:0006520 TAS:ProtIncPcellular amino acid metabolic process
GO:0006750 IEA:UniProtKB-KWPglutathione biosynthetic process
GO:0006749 TAS:UniProtKBPglutathione metabolic process
GO:0006954 IEA:EnsemblPinflammatory response
GO:0019370 ISS:UniProtKBPleukotriene biosynthetic process
GO:0006691 TAS:ReactomePleukotriene metabolic process
GO:0044281 TAS:ReactomePsmall molecule metabolic process
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_264461Aflatoxin activation and detoxification
REACT_147851Arachidonic acid metabolism
REACT_13433Biological oxidations
REACT_267633Defective ACY1 causes encephalopathy
REACT_268587Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
REACT_268321Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
REACT_268129Defective GGT1 causes Glutathionuria (GLUTH)
REACT_267887Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
REACT_268063Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
REACT_268256Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
REACT_267818Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
REACT_268027Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
REACT_268058Defective UGT1A1 causes hyperbilirubinemia
REACT_268618Defective UGT1A4 causes hyperbilirubinemia
REACT_116125Disease
REACT_6926Glutathione conjugation
REACT_6960Glutathione synthesis and recycling
REACT_267615Metabolic disorders of biological oxidation enzymes
REACT_111217Metabolism
REACT_22258Metabolism of lipids and lipoproteins
REACT_6959Phase II conjugation
REACT_150420Synthesis of Leukotrienes (LT) and Eoxins (EX)
  logo