MGP Database

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MGP001244

Ontology/Pathway Information

Entrez Gene ID2770
Gene Nameguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
Gene Symbol GNAI1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005813 IDA:UniProtKBCcentrosome
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005834 IBA:GO_CentralCheterotrimeric G-protein complex
GO:0005765 IDA:UniProtKBClysosomal membrane
GO:0030496 IDA:UniProtKBCmidbody
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0031683 IBA:GO_CentralFG-protein beta/gamma-subunit complex binding
GO:0031821 IBA:GO_CentralFG-protein coupled serotonin receptor binding
GO:0003924 IBA:GO_CentralFGTPase activity
GO:0005525 ISS:BHF-UCLFGTP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004871 IBA:GO_CentralFsignal transducer activity
GO:0007193 TAS:ReactomePadenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007188 IBA:GO_CentralPadenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0051301 IMP:UniProtKBPcell division
GO:0007186 ISS:BHF-UCLPG-protein coupled receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0043434 ISS:BHF-UCLPresponse to peptide hormone
GO:0007268 TAS:ReactomePsynaptic transmission
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_25330Activation of GABAB receptors
REACT_15333Adenylate cyclase inhibitory pathway
REACT_20653ADP signalling through P2Y purinoceptor 12
REACT_18339Adrenaline,noradrenaline inhibits insulin secretion
REACT_25031GABA B receptor activation
REACT_25199GABA receptor activation
REACT_19231G alpha (i) signalling events
REACT_19327G alpha (s) signalling events
REACT_19333G alpha (z) signalling events
REACT_19184GPCR downstream signaling
REACT_15457G-protein activation
REACT_15526G-protein mediated events
REACT_604Hemostasis
REACT_25282Inhibition of adenylate cyclase pathway
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_13685Neuronal System
REACT_15370Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
REACT_15295Opioid Signalling
REACT_798Platelet activation, signaling and aggregation
REACT_15426PLC beta mediated events
REACT_18325Regulation of insulin secretion
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_13477Transmission across Chemical Synapses
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