MGP Database

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MGP001249

Record overview

MGPD IDMGP001249
Gene ID2776
SpeciesHomo sapiens (Human)
Gene Nameguanine nucleotide binding protein (G protein), q polypeptide
Gene Symbol GNAQ
SynonymsGAQ; SWS; CMC1; G-ALPHA-q;
Alternate namesguanine nucleotide-binding protein G(q) subunit alpha; guanine nucleotide-binding protein alpha-q;
Chromosome9
Map Location9q21
SummaryThis locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.[provided by RefSeq, Nov 2010]
OrthologsView orthologs and multiple alignments for GNAQ

Proteins

guanine nucleotide-binding protein G(q) subunit alpha
Refseq ID:NP_002063
Protein GI:40254462
UniProt ID:P50148
mRNA ID:NM_002072
Length:359
RefSeq Status:
MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIP
YKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVI
FRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR
DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV
 
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