MGP Database

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MGP001249

Ontology/Pathway Information

Entrez Gene ID2776
Gene Nameguanine nucleotide binding protein (G protein), q polypeptide
Gene Symbol GNAQ
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 TAS:ProtIncCcytoplasm
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005834 IBA:GO_CentralCheterotrimeric G-protein complex
GO:0005765 IDA:UniProtKBClysosomal membrane
GO:0031965 IEA:UniProtKB-SubCellCnuclear membrane
GO:0005886 TAS:ReactomeCplasma membrane
GO:0031683 IBA:GO_CentralFG-protein beta/gamma-subunit complex binding
GO:0005096 IDA:UniProtKBFGTPase activator activity
GO:0003924 IBA:GO_CentralFGTPase activity
GO:0005525 IEA:UniProtKB-KWFGTP binding
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004871 IBA:GO_CentralFsignal transducer activity
GO:0031826 IBA:GO_CentralFtype 2A serotonin receptor binding
GO:0001508 IBA:GO_CentralPaction potential
GO:0007202 TAS:ProtIncPactivation of phospholipase C activity
GO:0007189 IBA:GO_CentralPadenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007596 TAS:ReactomePblood coagulation
GO:0048066 IEA:EnsemblPdevelopmental pigmentation
GO:0042733 IEA:EnsemblPembryonic digit morphogenesis
GO:0021884 IEA:EnsemblPforebrain neuron development
GO:0007215 IBA:GO_CentralPglutamate receptor signaling pathway
GO:0007507 IEA:EnsemblPheart development
GO:0042711 IEA:EnsemblPmaternal behavior
GO:0006469 IMP:BHF-UCLPnegative regulation of protein kinase activity
GO:0016322 IEA:EnsemblPneuron remodeling
GO:0060158 IBA:GO_CentralPphospholipase C-activating dopamine receptor signaling pathway
GO:0030168 TAS:ReactomePplatelet activation
GO:0043547 IDA:GOCPpositive regulation of GTPase activity
GO:0009791 IEA:EnsemblPpost-embryonic development
GO:0050821 IMP:BHF-UCLPprotein stabilization
GO:0035412 IMP:BHF-UCLPregulation of catenin import into nucleus
GO:0045634 IEA:EnsemblPregulation of melanocyte differentiation
GO:0001501 IEA:EnsemblPskeletal system development
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18405Acetylcholine regulates insulin secretion
REACT_19140ADP signalling through P2Y purinoceptor 1
REACT_19193Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
REACT_19375Free fatty acids regulate insulin secretion
REACT_18283G alpha (q) signalling events
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184GPCR downstream signaling
REACT_604Hemostasis
REACT_1505Integration of energy metabolism
REACT_111217Metabolism
REACT_798Platelet activation, signaling and aggregation
REACT_18325Regulation of insulin secretion
REACT_20524Signal amplification
REACT_14797Signaling by GPCR
REACT_111102Signal Transduction
REACT_21384Thrombin signalling through proteinase activated receptors (PARs)
REACT_20647Thromboxane signalling through TP receptor
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