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MGP001254

Record overview

MGPD IDMGP001254
Gene ID2782
SpeciesHomo sapiens (Human)
Gene Nameguanine nucleotide binding protein (G protein), beta polypeptide 1
Gene Symbol GNB1
Alternate namesguanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; G protein, beta-1 subunit; beta subunit, signal-transducing proteins GS/GI; transducin beta chain 1;
Chromosome1
Map Location1p36.33
SummaryHeterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
OrthologsView orthologs and multiple alignments for GNB1

Proteins

guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 1
Refseq ID:NP_002065
Protein GI:11321585
UniProt ID:P62873
mRNA ID:NM_002074
Length:340
RefSeq Status:
MSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWV
MTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV
SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
 
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 1
Refseq ID:NP_001269468
Protein GI:543173169
UniProt ID:P62873
mRNA ID:NM_001282539
Length:340
RefSeq Status:
Protein sequence is identical to GI:11321585 (mRNA isoform)
 
guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform 2
Refseq ID:NP_001269467
Protein GI:543173167
UniProt ID:P62873
mRNA ID:NM_001282538
Length:240
RefSeq Status:
MTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFV
SGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL
KADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
 
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