MGP Database

MGP001271

Ontology/Pathway Information

Entrez Gene ID	2806
Gene Name	glutamic-oxaloacetic transaminase 2, mitochondrial
Gene Symbol	GOT2
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0070062	IDA:UniProtKB	C	extracellular vesicular exosome
GO:0005743	IEA:Ensembl	C	mitochondrial inner membrane
GO:0005759	TAS:Reactome	C	mitochondrial matrix
GO:0005739	IDA:UniProtKB	C	mitochondrion
GO:0005886	IDA:UniProtKB	C	plasma membrane
GO:0016212	IEA:UniProtKB-EC	F	kynurenine-oxoglutarate transaminase activity
GO:0004069	IDA:UniProtKB	F	L-aspartate:2-oxoglutarate aminotransferase activity
GO:0080130	IEA:UniProtKB-EC	F	L-phenylalanine:2-oxoglutarate aminotransferase activity
GO:0044822	IDA:UniProtKB	F	poly(A) RNA binding
GO:0030170	IEA:InterPro	F	pyridoxal phosphate binding
GO:0006103	ISS:UniProtKB	P	2-oxoglutarate metabolic process
GO:0019470	TAS:BHF-UCL	P	4-hydroxyproline catabolic process
GO:0006532	IEA:Ensembl	P	aspartate biosynthetic process
GO:0006533	IDA:UniProtKB	P	aspartate catabolic process
GO:0006531	ISS:UniProtKB	P	aspartate metabolic process
GO:0005975	TAS:Reactome	P	carbohydrate metabolic process
GO:0008652	TAS:Reactome	P	cellular amino acid biosynthetic process
GO:0034641	TAS:Reactome	P	cellular nitrogen compound metabolic process
GO:0015908	IEP:UniProtKB	P	fatty acid transport
GO:0006094	TAS:Reactome	P	gluconeogenesis
GO:0006006	TAS:Reactome	P	glucose metabolic process
GO:0019551	IEA:Ensembl	P	glutamate catabolic process to 2-oxoglutarate
GO:0019550	IEA:Ensembl	P	glutamate catabolic process to aspartate
GO:0006536	ISS:UniProtKB	P	glutamate metabolic process
GO:0006107	IEA:Ensembl	P	oxaloacetate metabolic process
GO:0045471	IDA:UniProtKB	P	response to ethanol
GO:0044281	TAS:Reactome	P	small molecule metabolic process

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_238	Amino acid synthesis and interconversion (transamination)
REACT_116125	Disease
REACT_1520	Gluconeogenesis
REACT_723	Glucose metabolism
REACT_264090	Glycogen storage diseases
REACT_111217	Metabolism
REACT_13	Metabolism of amino acids and derivatives
REACT_474	Metabolism of carbohydrates
REACT_264430	Myoclonic epilepsy of Lafora

SMP Pathway Links

SMP ID	Description
SMP00136	2-Hydroxyglutric Aciduria (D And L Form)
SMP00243	4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency
SMP00357	Argininemia
SMP00003	Argininosuccinic Aciduria
SMP00002	Carbamoyl Phosphate Synthetase Deficiency
SMP00001	Citrullinemia Type I
SMP00072	Glutamate Metabolism
SMP00385	Homocarnosinosis
SMP00339	Hyperinsulinism-Hyperammonemia Syndrome
SMP00129	Malate-Aspartate Shuttle
SMP00205	Ornithine Transcarbamylase Deficiency (OTC Deficiency)
SMP00567	Succinic semialdehyde dehydrogenase deficiency
SMP00059	Urea Cycle