MGP Database

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MGP001272

Ontology/Pathway Information

Entrez Gene ID2810
Gene Namestratifin
Gene Symbol SFN
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0030659 TAS:ReactomeCcytoplasmic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0005615 TAS:ProtIncCextracellular space
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005634 IEA:UniProtKB-SubCellCnucleus
GO:0008426 TAS:ProtIncFprotein kinase C inhibitor activity
GO:0006915 TAS:ReactomePapoptotic process
GO:0061436 ISS:UniProtKBPestablishment of skin barrier
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0008630 IDA:HGNCPintrinsic apoptotic signaling pathway in response to DNA damage
GO:0031424 IEA:EnsemblPkeratinization
GO:0003334 IEA:EnsemblPkeratinocyte development
GO:0061024 TAS:ReactomePmembrane organization
GO:0043154 IDA:HGNCPnegative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010839 IEA:EnsemblPnegative regulation of keratinocyte proliferation
GO:0006469 TAS:ProtIncPnegative regulation of protein kinase activity
GO:0071901 TAS:GOCPnegative regulation of protein serine/threonine kinase activity
GO:0030307 IEA:EnsemblPpositive regulation of cell growth
GO:0045606 ISS:UniProtKBPpositive regulation of epidermal cell differentiation
GO:0046827 IEA:EnsemblPpositive regulation of protein export from nucleus
GO:1900740 TAS:ReactomePpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0000079 IEA:EnsemblPregulation of cyclin-dependent protein serine/threonine kinase activity
GO:0010482 ISS:UniProtKBPregulation of epidermal cell division
GO:0001836 IDA:HGNCPrelease of cytochrome c from mitochondria
GO:0007165 TAS:ProtIncPsignal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_549Activation of BAD and translocation to mitochondria
REACT_697Activation of BH3-only proteins
REACT_578Apoptosis
REACT_964Intrinsic Pathway for Apoptosis
REACT_11123Membrane Trafficking
REACT_268456Programmed Cell Death
REACT_147867Translocation of GLUT4 to the plasma membrane
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